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	Provedor de dados BJMBR (1) Genet. Mol. Biol. (1) Autor Bader,M. (1) Wang,Yi-Hong (1) Warren Jr.,James T. (1) Palavra-chave Knockout (2) Animal models (1) Arabidopsis thaliana (1) Downy mildew resistance (1) Renin-angiotensin system (1) Retrotransposon (1) Transgenic (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2010 (1) 1998 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Mutations in retrotransposon AtCOPIA4 compromises resistance to Hyaloperonospora parasitica in Arabidopsis thaliana Genet. Mol. Biol. Wang,Yi-Hong; Warren Jr.,James T.. Retrotransposons (RTEs) are a principal component of most eukaryotic genomes, representing 50%-80% of some grass genomes. RTE sequences have been shown to be preferentially present in disease resistance gene clusters in plants. Arabidopsis thaliana has over 1,600 annotated RTE sequences and 56 of these appear to be expressed because of the exact expressed sequence tag (EST) matches and the presence of intact open reading frames. Of the 22 represented in the Affymetrix ATH1 array, AtCOPIA4 was found to be expressed at a higher level than all other RTEs across different developmental stages. Since AtCOPIA4 is located in the RPP5 gene cluster and is adjacent to RPP4 which confers resistance to the downy mildew oomycete Hyaloperonospora parasitica isolate... Tipo: Info:eu-repo/semantics/article Palavras-chave: Arabidopsis thaliana; Retrotransposon; Downy mildew resistance; Knockout. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000100023 Transgenic animal models for the functional analysis of vasoactive peptides BJMBR Bader,M.. The interplay of vasoactive peptide systems is an essential determinant of blood pressure regulation in mammals. While the endothelin and the renin-angiotensin systems raise blood pressure by inducing vasoconstriction and sodium retention, the kallikrein-kinin and the natriuretic-peptide systems reduce arterial pressure by eliciting vasodilatation and natriuresis. Transgenic technology has proven to be very useful for the functional analysis of vasoactive peptide systems. As an outstanding example, transgenic rats overexpressing the mouse Ren-2 renin gene in several tissues become extremely hypertensive. Several other transgenic rat and mouse strains with genetic modifications of components of the renin-angiotensin system have been developed in the past... Tipo: Info:eu-repo/semantics/article Palavras-chave: Renin-angiotensin system; Transgenic; Animal models; Knockout. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000900011 Registros recuperados: 2 Primeira ... 1 ... Última

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