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Registros recuperados: 29
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Adiponectin promoter polymorphisms are predictors of lipid profile improvement after bariatric surgery Genet. Mol. Biol.
Gasparotto,Aline Simas; Borges,Diego Olschowsky; Zandoná,Marília Remuzzi; Ramos,Mauricio Jacques; Meihnardt,Nelson Guardiola; Mattevi,Vanessa S..
Abstract Our aim was to investigate if single nucleotide polymorphisms (SNPs) located in the 5′ regions of leptin (LEP, -2548 G > A, rs7799039), resistin (RETN, -420 C > G, rs1862513) and adiponectin (ADIPOQ, -11391 G > A, rs17300539 and -11377 C > G, rs266729) genes were related to changes in body mass index (BMI) and metabolic variables after bariatric surgery in 60 extremely obese individuals. At baseline, ADIPOQ -11391 A-allele carriers showed higher plasma adiponectin and lower total cholesterol levels when compared to G/G homozygotes. Approximately 32 months post-surgery, a mean reduction of 35% in BMI and an important improvement in metabolic profiles were observed. In addition, for the ADIPOQ -11377 polymorphism, a higher decrease in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adiponectin; Polymorphism; Obesity; Lipid profile; Bariatric surgery.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000500736
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Association of serum lipid components and obesity with genetic ancestry in an admixed population of elderly women Genet. Mol. Biol.
Lins,Tulio C.; Pires,Alause S.; Paula,Roberta S.; Moraes,Clayton F.; Vieira,Rodrigo G.; Vianna,Lucy G.; Nobrega,Otávio T.; Pereira,Rinaldo W..
The prevalence of metabolic disorders varies among ethnic populations and these disorders represent a critical health care issue for elderly women. This study investigated the correlation between genetic ancestry and body composition, metabolic traits and clinical status in a sample of elderly women. Clinical, nutritional and anthropometric data were collected from 176 volunteers. Genetic ancestry was estimated using 23 ancestry-informative markers. Pearsons correlation test was used to examine the relationship between continuous variables and an independent samples t-test was used to compare the means of continuous traits within categorical variables. Overall ancestry was a combination of European (57.49%), Native American (25.78%) and African (16.73%)....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dyslipidemia; Genetic ancestry; Lipid profile; Obesity; Postmenopausal women.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000400005
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Polymorphisms FTO rs9939609, PPARG rs1801282 and ADIPOQ rs4632532 and rs182052 but not lifestyle are associated with obesity related-traits in Mexican children Genet. Mol. Biol.
Muñoz-Yáñez,C; Pérez-Morales,R; Moreno-Macías,H; Calleros-Rincón,E; Ballesteros,G; González,R. A; Espinosa,J.
Abstract Concerning the genetic factors of obesity, no consistent association between populations has been reported, which may be due to the frequency of polymorphisms, the lifestyle of studied populations and its interaction with other factors. We studied a possible association of polymorphisms FTO rs9939609, PPARG rs1801282, and ADIPOQ rs4632532 and rs182052 with obesity phenotypes in 215 Mexican children. Glucose, triglycerides, cholesterol, HDL and LDL were measured. In addition, weight, height, waist circumference and triceps skin thickness were recorded. High-energy diets and sedentary behavior were evaluated with a validated questionnaire. In contrast with other reports, only FTO rs9939609 was associated with obesity related-traits, including BMI (p...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Obesity; Children; Polymorphisms; Energy intake; Physical activity; Lipid profile.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000400547
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Wreckfish (Polyprion americanus). New Knowledge About Reproduction, Larval Husbandry, and Nutrition. Promise as a New Species for Aquaculture ArchiMer
Pérez, Evaristo; Linares, Fátima; Rodríguez Villanueva, José; Vilar, Antonio; Mylonas, Constantinos; Fakriadis, Ioannis; Papadaki, Maria; Papandroulakis, Nikos; Papadakis, Ioannis; Robles, Rocío; Fauvel, Christian; Roo, Javier; Peleteiro, José; Lluch, Nuria; Pazos, Gema; Méndez, Belén; Sigelaki, Irini; Gómez, Castora; Pérez, Montse; Álvarez-blázquez, Blanca.
Four different wreckfish (Polyprion americanus) broodstock batches were maintained in research facilities under different photo and thermo-period conditions, one in Greece, the Helenic Center for Marine Research (HCMR, n = 3) and three in Spain: Instituto Español de Oceanografía (IEO, n = 13) in Vigo, Aquarium Finisterrae (MC2, n = 21) in A Coruña and Consellería do Mar (CMRM, n = 11). The CMRM includes two centers that work together: Instituto Galego de Formación en Acuicultura (IGAFA) and Centro de Investigacións Mariñas (CIMA), both in Pontevedra. During the five years of the project DIVERSIFY (Exploring the biological and socio-economic potential of new-emerging candidate fish species for the expansion of the European aquaculture industry, 2013–2018)...
Tipo: Text Palavras-chave: Wreckfish; Broodstock; Larval husbandry; Nutrition; Natural spawns; Live prey; Lipid profile; Ontogeny.
Ano: 2019 URL: https://archimer.ifremer.fr/doc/00660/77192/78615.pdf
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Beneficial Effects of Exercise Training (Treadmill) on Body Mass and Skeletal Muscle Capillaries/Myocyte Ratio in C57BL/6 Mice Fed High-Fat Diet International Journal of Morphology
Motta,Victor Faria; Mandarim de Lacerda,Carlos Alberto.
C57BL/6 mice develop signals and symptoms comparable at least in part with the metabolic syndrome in humans. This study aimed to evaluate the beneficial effects of exercise training upon skeletal microcirculation in these mice. Animals were fed one of two diets during an eight week period: standard chow (SC) or very high-fat (HF). Afterwards, the exercise training protocol (treadmill) was established and mice divided into SC and HF sedentary (SC-Sed, HF-Sed) or exercised groups (SC-Ex, HF-Ex), respectively. HF/HF-Sed mice had the greatest body mass (plus 65% than SC-Sed; P<0.0001), and exercise reduced it by 23% (P<0.0001). The plasma insulin was higher in the HF-Sed than in the matched ­Ex (P<0.001). The ratio between capillaries/myocytes in...
Tipo: Journal article Palavras-chave: Aerobic training; Metabolic syndrome; Lipid profile; Skeletal muscle.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100037
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Mixed crude glycerin in laying hen diets: live performance and egg quality and fatty acid profile Rev. Bras. Ciênc. Avic.
Duarte,CRA; Murakami,AE; Boso,KMO; Eyng,C; Ospina-Rojas,IC; Matumoto-Pintro,PT.
This study evaluated the performance and the quality and fatty acid profile of eggs from laying hens fed diets containing mixed crude glycerin (MCG; 80% vegetable fat + 20% animal fat). A total of 240 39-week-old Hy-Line W36 laying hens were distributed according to a completely randomized experimental design into six treatments consisting of graded MCG dietary inclusion levels (0, 1.5, 3.0, 4.5, 6.0, and 7.5%), with five replicates of eight birds each. Feed intake linearly decreased (p<0.05) with increasing MCG inclusion levels. The percentages of myristic, palmitic, and α-linolenic acids in the eggs linearly decreased as MCG dietary levels increased (p<0.05), while α-linoleic acid, polyunsaturated fatty acids (PUFA) and ω-6/ω-3 ratio linearly...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Excreta moisture; Eggs; Fatty acids; Glycerin; Glycerol; Lipid profile.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2014000400003
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Performance, abdominal fat deposition and bone characteristics of broilers fed diets containing different lipid sources Rev. Bras. Ciênc. Avic.
Potença,A; Murakami,AE; Fernandes,JIM; Matsushita,M; Nakagawa,EL.
Two experiments were carried out to evaluate the performance, abdominal fat yield, and bone parameters of broiler chickens fed diets containing different lipid feedstuffs as energy source. During the starter phase (1 to 21 days) of Experiment 1, a completely randomized design with four treatments with eight replicates of 49 birds each one was applied. Broilers were fed starter diets formulated with different lipid sources: soybean oil (SO), cottonseed oil (CO), poultry offal oil (PO), and beef tallow (BT). During the finisher phase (21 to 42 days) of Experiment 1, each initial treatment was divided in two experimental groups: one fed the same fat ingredient as the previous period, and the other fed SO as energy source. Thus, during this period, a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Abdominal fat deposition; Bone parameters; Lipid profile; Performance.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2008000400008
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Feed training of giant trahira fingerlings fed diets containing different levels of vitamin C R. Bras. Zootec.
Kasai,Rodrigo Yutaka Dichoff; Salaro,Ana Lúcia; Zuanon,Jener Alexandre Sampaio; Sabarense,Céphora Maria; Tavares,Mateus Moraes; Campelo,Daniel Abreu Vasconcelos.
The objective of this work was to evaluate suplemenation of vitamin C during feed training of giant trahira fingerlings. An experiment was established in a complete random design with seven treatments (0.0, 17.5, 52.5, 87.5, 122.5, 175.0 and 350.0 mg vitamin C/kg diet) and four repetitions. Giant trahira fingerlings (2.8 ± 0.2 cm) were distributed in 6-L aquaria at the density of 6 fish/L. A basal diet was formulated with 44.0% of crude protein and vitamin C and bovine heart were added in it daily. After 20 days, biometry of fish for evaluation of weight and length gains, rates of survival and cannibalism and uniformity of final length and for macroscopic observations of clinical signs of deficiency or excess of vitamin was carried out. After biometry...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cannibalism; Carnivorous fish; Hoplias lacerdae; Length uniformity; Lipid profile.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982011000300001
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Oocyte production in Nellore cows supplemented with long-chain fatty acid soaps R. Bras. Zootec.
Souza,Moacir Rogério de; Santos,Geraldo Tadeu dos; Lima,Luciano Soares de; Mazucheli,Josmar; Zeoula,Lúcia Maria; Rigolon,Luiz Paulo; Cavalieri,Fábio Luiz Bim.
ABSTRACT This study was conducted to evaluate the effects of long-chain fatty acid soaps (LCFAS) of soybean oil on the production and quality of aspirated cumulus-oocyte complexes (COC) of lactating Nellore (Bos taurus indicus) cows. The effects of LCFAS on the plasma concentration of lipoproteins, total cholesterol, triacylglycerol, urea N, and insulin were also addressed. Thirty lactating Nellore cows were randomly assigned to one of two dietary groups. Cows were grazed on a Tifton 85 pasture throughout the experiment (100 days). Treatments consisted of a supplement with no fat included (CONT); and a supplement containing 47.2 g/kg of LCFAS on a dry matter basis. After 14 days of treatment, animals were subjected to 4.93±1.55 rounds of consecutive ovum...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Beef cattle; Insulin; Fat supplementation; Lipid profile; Ovum pick up.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982016000300138
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Influence of animal fat substitution by vegetal fat on Mortadella-type products formulated with different hydrocolloids Scientia Agricola
Saldaña,Erick; Lemos,Ana Lúcia da Silva Corrêa; Selani,Miriam Mabel; Spada,Fernanda Papa; Almeida,Marcio Aurélio de; Contreras-Castillo,Carmen Josefina.
Meat has played a crucial role in human evolution and is an important component of a healthy and well-balanced diet on account of its nutritional properties, its high biological value as a source of protein, and the vitamins and minerals it supplies. We studied the effects of animal fat reduction and substitution by hydrogenated vegetal fat, sodium alginate and guar gum. Fatty acid composition, lipid oxidation, color and instrumental texture as well as the sensorial difference between low, substituted-fat and the traditional formulations for mortadella-type products were analyzed. Both substitution and reduction of animal fat decreased the saturated fatty acids percentage from 40% down to 31%. A texture profile analysis showed differences between the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lipid profile; Lipid oxidation; Fat-replacers; Fat vegetal; Texture.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162015000600495
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Fish by-product meal in diets for commercial laying hens Animal Sciences
Silva, André Ferreira; Cruz, Frank George Guimarães; Rufino, João Paulo Ferreira; Miller, Waldo Mateus Plácido; Flor, Nathália Siqueira; Assante, Rafael Torres.
 This study aimed to evaluate the increasing levels (0, 1, 2, 3 e 4%) of fish by-product meal in diets for laying hens on performance, egg quality and economic analysis. A total of 160 Dekalb White hens with 52-wk old were distributed in a completely randomized design with five treatments and four replicates of eight birds each. The experiment lasted 84 days divided into four periods of 21 days. Estimates of fish by-product meal levels were determined by polynomial regression. Differences (p < 0.05) were detected for all variables of performance, in egg weight, yolk and albumen percentage, yolk and albumen height, feed cost and production cost, in which the inclusion of fish by-product meal in the diets showed better results. It can be concluded that...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Alternative feed; Economic available; Feed cost; Lipid profile; Performance..
Ano: 2017 URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/34102
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Improvement of friable callus production of Boerhaavia paniculata Rich and the investigation of its lipid profile by GC/MS Anais da ABC (AABC)
SOUZA,JOANNE M.M.; BERKOV,STRAHILL; SANTOS,ALBERDAN S..
In this study, a protocol to induce high amount of friable callus of Boerhaavia paniculata RICH and a lipidomics technique were applied to investigate the profile of lipids to relate to those present in the roots of this plant that presented anti-inflammatory activity in the crude hexane extract. The callus culture was induced from seeds in solidified Murashige and Skoog medium containing different amounts of glucose and different concentrations of 2,4-Dichlorophenoxyacetic acid. The explants were kept in a germination chamber at 30±2°C with a photoperiod of 16 h under light intensity of 27 µmol m–2 s–1 for 4 weeks. The best results for friable callus formation and development of the biomass were obtained in the treatment containing 2.26 µM 2.4-D and...
Palavras-chave: Anti-inflammatory lipids; Boerhaavia paniculata; Callus culture; Lipid profile; Medicinal plant.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000301015
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Effect of Bauhinia holophylla treatment in Streptozotocin-induced diabetic rats Anais da ABC (AABC)
PINHEIRO,MARCELO S.; RODRIGUES,LUHARA S.; S. NETO,LEILA; MORAES-SOUZA,RAFAIANNE Q.; SOARES,THAIGRA S.; AMÉRICO,MADILEINE F.; CAMPOS,KLEBER E.; DAMASCENO,DÉBORA C.; VOLPATO,GUSTAVO T..
ABSTRACT Bauhinia holophylla, commonly known as “cow’s hoof”, is widely used in Brazilian folk medicine for the diabetes treatment. Therefore, the aim of this study was at evaluating the aqueous extract effect of Bauhinia holophylla leaves treatment on the streptozotocin-induced diabetic rats. Diabetes was induced by Streptozotocin (40 mg/Kg) in female Wistar rats. Oral administration of aqueous extract of Bauhinia holophylla leaves was given to non-diabetic and diabetic rats at a dose of 400 mg/kg during 21 days. On day 17 of treatment, the Oral Glucose Tolerance Test was performed to determine the area under the curve. At the end of the treatment, the animals were anesthetized and blood was collected for serum biochemical parameters analysis. After...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bauhinia holophylla; Diabetes; Lipid profile; Medicinal plants; Rats..
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100263
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The effects of coconut oil supplementation on the body composition and lipid profile of rats submitted to physical exercise Anais da ABC (AABC)
RESENDE,NATHÁLIA M.; FÉLIX,HENRIQUE R.; SORÉ,MURILLO R.; M.M. NETO,ANÍBAL; CAMPOS,KLEBER E.; VOLPATO,GUSTAVO T..
This study aims to verify the effects of coconut oil supplementation (COS) in the body composition and lipid profile of rats submitted to physical exercise. The animals (n=6 per group) were randomly assigned to: G1=Sedentary and Non-supplemented (Control Group), G2=Sedentary and Supplemented, G3=Exercised and Non-supplemented and G4=Exercised and Supplemented. The COS protocol used was 3 mL/Kg of body mass by gavage for 28 days. The physical exercise was the vertical jumping training for 28 days. It was determined the body mass parameters, Lee Index, blood glucose and lipid profile. The COS did not interfere with body mass, but the lean body mass was lower in G3 compared to G2. The final Lee Index classified G1 and G2 as obese (>30g/cm). The lipid...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cocos nucifera; LDL-c/HDL-c ratio; Lipid profile; Nutrition; Rats; Vertical jumping training.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000300933
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Influence of hesperidin and vitamin C on glycemic parameters, lipid profile, and DNA damage in rats treated with sucrose overload Anais da ABC (AABC)
FRANKE,SILVIA I.R.; MOLZ,PATRÍCIA; MAI,CAMILA; ELLWANGER,JOEL H.; ZENKNER,FERNANDA F.; HORTA,JORGE A.; PRÁ,DANIEL.
ABSTRACT We evaluated the influence of hesperidin and vitamin C (VitC) on glycemic parameters, lipid profile, and DNA damage in male Wistar rats treated with sucrose overload. Rats were divided into six experimental groups: I-water control; II-sucrose control; III-hesperidin control; IV-VitC control; V-co-treatment of sucrose plus hesperidin; VI-co-treatment of sucrose plus VitC. We measured the levels of triglycerides, total cholesterol, HDL-c, LDL-c, fasting glucose, and glycated hemoglobin (A1C). DNA damage was evaluated in blood and brain cells using the comet assay and the micronucleus test was used to evaluate chromosomal damages in the rat bone marrow. Co-treatment with VitC, but not with hesperidin, normalized the serum glucose. No effect of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: DNA damage; Hesperidin; Glycated hemoglobin; Lipid profile; Sucrose; Vitamin C.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000502203
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Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity Anais da ABC (AABC)
Nascimento,Ozanildo V; Boleti,Ana P.A; Yuyama,Lucia K.O; Lima,Emerson S.
Amazonian Camu-camu fruit (Myrciaria dubia HBK Mc Vaugh) has attracted interest from food and cosmetics industries because of its rich content of vitamin C, flavonoids and anthocyanins. The goal of this study was investigates the antiobesity action of the ingestion of the Camu-camu pulp in a rat model of diet-induced obesity. Wistar rats with obesity induced by subcutaneous injection of monosodium glutamate receiving diet ad libitum. The rats were divided in two groups: an experimental group that ingested 25 mL/day of Camu-camu pulp (CCG) and a non treated group (CG). After 12 weeks, the animals were sacrificed. Blood, liver, heart, white adipose tissues were collected and weighted, biochemical and inflammatory profiles were determinate as well. Animals...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Amazonian fruit; Flavonoids; Lipid profile; Myrciaria dubia; Obesity.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000100355
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Impact of the Training Program on Lipid Profile and Cardiac Health Biol. Res.
BURNEIKO,REGINA COELI; DINIZ,YEDA SANT'ANA; FAINE,LUCIANE APARECIDA; MACHADO GALHARDI,CRISTIANO; PADOVANI,CARLOS ROBERTO; NOVELLI,ETHEL LOURENZI B.; CICOGNA,ANTONIO CARLOS.
The aim of this study was to investigate the effects of training programs on serum lipid profile and myocardial oxidative stress. Male Wistar rats (2 mo-old) were divided into three groups (n=8): sedentary (S), loadless trained (T) and trained-overload 2% body weight (TL). T and TL were trained through swimming for 9 weeks. T and TL rats had increased myocardial lipoperoxide (TBA) and lipid hydroperoxide (HP), whereas HP was higher in TL than in T animals. Superoxide dismutase (SOD) activities were lowest in TL. Myocardial glutathione peroxidase (GSH-Px) was lower in TL than in T and S rats. TL decreased HDL-cholesterol and increased LDL-cholesterol. The serum lactate dehydrogenase and TBA were increased, while SOD and GSH-Px activities were decreased in...
Tipo: Journal article Palavras-chave: Training; Lipid profile; Oxidative stress; Heart; Serum.
Ano: 2004 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000100006
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Effect of an aqueous extract of annatto (Bixa orellana) seeds on lipid profile and biochemical markers of renal and hepatic function in hipercholesterolemic rats BABT
Paula,Heberth de; Pedrosa,Maria Lúcia; Rossoni Júnior,Joamyr Victor; Haraguchi,Fabiano Kenji; Santos,Rinaldo Cardoso dos; Silva,Marcelo Eustáquio.
Annatto extract is a natural food color obtained from the outer coatings of the seeds of the Annatto tree (Bixa orellana L.). This is the first report in the literature that shows the relationship between the aqueous annatto extract and its influence on lipid profile in animals. Male Fisher rats were divided into three groups (n=12): C group, fed standard diet and water; H group, fed high-lipid diet and water and; HU group, with high-lipid diet and aqueous annatto extract for 60 days. The treatment with annatto extract in animals fed with the high-lipid diet lowered the LDL- and total cholesterol and raised the HDL-cholesterol, suggesting a hypocholesterolemic effect. Neither high-fat diet nor aqueous annatto extract had any significant effect on serum...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Annatto; Bixa orellana; Cholesterol; Rat; Aqueous extract; Lipid profile.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000600008
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Whey protein improves HDL/non-HDL ratio and body weight gain in rats subjected to the resistance exercise BABT
Teixeira,Kely Raspante; Silva,Marcelo Eustáquio; Neves,Leandro Xavier; Santos,Rinaldo Cardoso dos; Pedrosa,Maria Lúcia; Haraguchi,Fabiano Kenji.
The aim of this study was to evaluate the effects of resistance exercise, such as weight-lifting (WL) on the biochemical parameters of lipid metabolism and cardiovascular disease risk in the rats fed casein (control) or whey protein (WP) diets. Thirty-two male Fisher rats were randomly assigned to sedentary or exercise-trained groups and were fed control or WP diets. The WL program consisted of inducing the animals to perform the sets of jumps with weights attached to the chest. After seven weeks, arteriovenous blood samples were collected for analysis. The WL or WP ingestion were able to improve the lipid profile, reducing the TC and non-HDL cholesterol concentrations, but only WP treatment significantly increased the serum HDL concentrations, thereby...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dietary protein; Lipid profile; Cholesterol; Cardiovascular disease risk.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000600019
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Evaluation of lipid profile and oxidative stress in STZ-induced rats treated with antioxidant vitamin BABT
Almeida,Danielle Ayr Tavares de; Braga,Camila Pereira; Novelli,Ethel Lourenzi Barbosa; Fernandes,Ana Angélica Henrique.
The present study investigated the effect of supplementation of vitamin E on streptozotocin (STZ)-induced diabetic rats by measuring blood glucose, changes in body weight, food and water intake, lipid profile, serum urea and creatinine level, and antioxidant enzyme activity. Male Wistar rats were divided into four groups: control rats (GI); rats receiving vitamin E (GII); STZ-induced diabetic rats (GIII) and STZ-induced diabetic rats treated with vitamin E (GIV). Vitamin E reduced (p<0.05) blood glucose and urea, improved the lipid profile (decreased the serum levels of total cholesterol, LDL cholesterol, VLDL cholesterol and triacylglycerols, and increased HDL cholesterol) and increased total protein in STZ-induced diabetic rats (GIV). Vitamin...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Vitamin E; Lipid profile; Oxidative stress; STZ.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000400007
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