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| Lemos,Odilon A.; Sanches,Júlio C.M.; Silva,Ícaro E.F.; Silva,Márcio L.A.; Vinhólis,Adriana H.C.; Felix,Mireille A.P.; Santos,Raquel A.; Cecchi,Andréa O.. |
| Tabebuia sp. is native to tropical rain forests throughout Central and South America. Although the biological and pharmacological effects of bark extracts have been intensely studied, little is known on the extract obtained from the flower. Herein, the genotoxic potential of a flower extract from T. impetiginosa ("ipê roxo") on the blood and liver cells of Wistar rats was evaluated. Experimental procedures involved only male animals. Graduated concentrations of the extract, viz., 100, 300 and 500 mg kg-1 of body weight, were gavage-administered and 24 h latter cells were collected and processed for analysis. With the exception of the 100 mg kg-1 dose, a significant increase in DNA damage was noted, when compared with a negative control group. Although the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tabebuia impetiginosa; Comet assay; Wistar rats; Natural compounds. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000300017 |
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| ALI,A.; JAVAID,A.; SHOAIB,A.. |
| ABSTRACT Sclerotium rolfsii is a soil-borne fungal plant pathogen that causes diseases in more than 500 plant species. Chemical fungicides used to control this disease cause environmental pollution, therefore, plant derived compounds can be used as alternative to synthetic fungicides to reduce environmental pollution. Chenopodium album is a weed of family Chenopodiaceae that is used as food and also has medicinal importance. In the present study, antifungal activity of methanolic root extract of C. album was evaluated against S. rolfsii using six concentrations viz. 0.5, 1.0, 1.5, 2.0, 2.5 and 3.0 g 100 mL-1 amended in malt extract as growth medium. All the root extract concentrations significantly reduced fungal biomass by 15-58% over control. Gas... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biological control; Natural compounds; Reduction use of agrochemical. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582017000100245 |
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| Ospina Medina,Luisa; Álvarez Gómez,Ángela; Cortés Mancera,Fabian; Cadavid Jaramillo,Ángela; Cardona Maya,Walter. |
| Introduction: there are natural products from different fruits and plants that are effective as spermicides, but it is important that they should have little or no cytotoxic effect on epithelial cells. Currently available spermicides with nonoxynol-9 cause vaginal irritation and damage to the vaginal mucosa, the uterine epithelium, and the microbial flora of the vagina. Objective: to elucidate the effect on cell viability, cytotoxicity and apoptosis of spermicidal extracts of Ananas comosus (L.) Merr. and Sapindus saponaria L. over HeLa cell line. Methods: both extracts were evaluated on HeLa cell line using the novel ApoTox-Glo™ Triplex Assay to determine whether cell viability, cytotoxicity and apoptosis were affected. Results: it was... |
| Tipo: Journal article |
Palavras-chave: Natural compounds; Spermicides; Cell cytotoxicity; Cell viability; Cell apoptosis; Ananas comosus; Sapindus saponaria. |
| Ano: 2013 |
URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962013000400005 |
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