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Nunomura,Rita de Cássia Saraiva; Silva,Ellen Cristina Costa da; Oliveira,Denilson Ferreira; Garcia,Adriana Mello; Boeloni,Jankerle Neves; Nunomura,Sergio Massayoshi; Pohlit,Adrian Martin. |
1300 ppm (1.3 g / L), water and ethanol extracts prepared from stems or roots of Picrolemma sprucei Hook. f. were lethal (85-90 % mortality) in vitro to Haemonchus contortus (Barber Pole Worm) larvae, a gastrointestinal nematode parasite found in domestic and wild ruminants. Neosergeolide and isobrucein B were isolated in 0.0083 and 0.0070 % yield from dry, ground P. sprucei stems (0.89 kg). Neosergeolide, isobrucein B and the anthelmintic drug standard levamisole all caused comparable mortality rates (68-77 %) in vitro to H. contortus at similar concentrations (81-86 ppm). The anthelmintic activity of P. sprucei infusions (teas), alcohol extracts, and neosergeolide and isobrucein B, has therefore been demonstrated for the first time. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Picrolemma pseudocoffea Ducke; Haemonchus contortus; Neosergeolide; Isobrucein B; Caferana. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672006000300006 |
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