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| Linden,R.; Chiarini,L.B.. |
| Programmed cell death in the form of apoptosis involves a network of metabolic events and may be triggered by a variety of stimuli in distinct cells. The nervous system contains several neuron and glial cell types, and developmental events are strongly dependent on selective cell interactions. Retinal explants have been used as a model to investigate apoptosis in nervous tissue. This preparation maintains the structural complexity and cell interactions similar to the retina in situ, and contains cells in all stages of development. We review the finding of nuclear exclusion of several transcription factors during apoptosis in retinal cells. The data reviewed in this paper suggest a link between apoptosis and a failure in the nucleo-cytoplasmic partition of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Programmed cell death; Retina; Neurogenesis; Development; Nuclear membrane. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000700003 |
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| Parnavelas,J.G.. |
| Neurons of the mammalian cerebral cortex comprise two broad classes: pyramidal neurons, which project to distant targets, and the inhibitory nonpyramidal cells, the cortical interneurons. Pyramidal neurons are generated in the germinal ventricular zone, which lines the lateral ventricles, and migrate along the processes of radial glial cells to their positions in the developing cortex in an `inside-out' sequence. The GABA-containing nonpyramidal cells originate for the most part in the ganglionic eminence, the primordium of the basal ganglia in the ventral telencephalon. These cells follow tangential migratory routes to enter the cortex and are in close association with the corticofugal axonal system. Once they enter the cortex, they move towards the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neurogenesis; Migration; Cortical development. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001200003 |
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| Geffroy, Benjamin; Sadoul, Bastien; Bouchareb, Amine; Prigent, Sylvain; Bourdineaud, Jean-paul; Gonzalez-rey, Maria; Morais, Rosana N.; Mela, Maritana; Carvalho, Lucelia Nobre; Bessa, Eduardo. |
| Nature-based tourism is gaining extensive popularity, increasing the intensity and frequency of human-wildlife contacts. As a consequence, behavioral and physiological alterations were observed in most exposed animals. However, while the majority of these studies investigated the effects of punctual exposure to tourists, the consequences of constant exposition to humans in the wild remains overlooked. This is an important gap considering the exponential interest for recreational outdoor activities. To infer long-term effects of intensive tourism, we capitalized on Odontostilbe pequira, a short-lived sedentary Tetra fish who spends its life close to humans, on which it feeds on dead skin. Hence, those fish are constantly exposed to tourists throughout their... |
| Tipo: Text |
Palavras-chave: Coping style; Ecotourism; Conservation; Behavior; Gene expression; Cortisol; Neurogenesis; Fish. |
| Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00423/53470/54366.pdf |
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| Sadoul, Bastien; Alfonso, Sebastien; Bessa, E.; Bouchareb, A.; Blondeau-bidet, E.; Clair, P.; Chatain, Beatrice; Begout, Marie-laure; Geffroy, Benjamin. |
| Stress enhances or inhibits neurogenesis in mammals and some fish species. The link between the two processes is still unclear. Most studies have been performed in very specific stressful or altered environments. Despite the known inter-individual divergence in coping abilities within populations, the relationship between the stress axis and neurogenesis has never been addressed in unstressed individuals. Here we correlate brain expression of the pcna (proliferating cell nuclear antigen) and neurod1 (neurogenic differentiation factor 1) genes, two markers of neurogenesis, with transcripts of cortisol receptors in three fish species living in very distinct environments. Within the three species, individuals with the highest expression of neurogenesis genes... |
| Tipo: Text |
Palavras-chave: Neurogenesis; Stress; Glucocorticoid receptor; Mineralocorticoid receptor; Hypothalamo-pituitary-interrenal axis. |
| Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00444/55560/57164.pdf |
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| Khoshbin khoshnazar,A. R; Jahanshahi,M; Azami,N. S. |
| Radiation therapy of the brain is associated with many consequences, including cognitive disorders. Pathogenesis of radiation induced cognitive disorder is not clear, but reduction of neurogenesis in hippocampus may be an underlying reason. 24 adult male rats entered to study. Radiation absorbed dose to midbrain was 10 Gy, delivered by routine cobalt radiotherapy machine which its output was measured 115.24 cGy/min. The rats were divided in four groups of sixes, including groups of control, single fraction 10 Gy, fractionated 10 Gy and finally anaesthesia sham group. Number of pyramidal nerve cells was counted in two regions of hippocampus formation (CA1 and CA3). The radiation could reduce the number of cells in two regions of hippocampus significantly... |
| Tipo: Journal article |
Palavras-chave: Hippocampus; Neurogenesis; Radiation; Fractionation. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100026 |
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