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Nuclear exclusion of transcription factors associated with apoptosis in developing nervous tissue BJMBR
Linden,R.; Chiarini,L.B..
Programmed cell death in the form of apoptosis involves a network of metabolic events and may be triggered by a variety of stimuli in distinct cells. The nervous system contains several neuron and glial cell types, and developmental events are strongly dependent on selective cell interactions. Retinal explants have been used as a model to investigate apoptosis in nervous tissue. This preparation maintains the structural complexity and cell interactions similar to the retina in situ, and contains cells in all stages of development. We review the finding of nuclear exclusion of several transcription factors during apoptosis in retinal cells. The data reviewed in this paper suggest a link between apoptosis and a failure in the nucleo-cytoplasmic partition of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Programmed cell death; Retina; Neurogenesis; Development; Nuclear membrane.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000700003
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Mg 2+ -dependent ATPase activity in triatomine salivary glands (Heteroptera, Triatominae) Iheringia, Sér. Zool.
Anhê,Ana C. B. M.; Azeredo-Oliveira,Maria T. V..
ABSTRACT Mg2+-ATPase activity was detected in the three salivary glands of adult triatomines, males and females, of Triatoma infestans (Klug, 1834) and Panstrongylus megistus (Burmeister, 1835) (Heteroptera, Triatominae). A predominance of binucleated cells in D1 and D2 and mononucleated in D3 was observed, with bulky and polyploidy nuclei. ATPase activity was detected in the nuclei, possibly in euchromatin and nucleolus, where this enzyme probably acts in the transcription process. ATPase reaction was also evidenced in the nuclear membrane, which is probably associated with nuclear-cytoplasmatic transport. These characteristics indicate a high metabolism and protein synthesis, which must be essential to saliva production as well as in maintaining the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Euchromatin; Gland; Nuclear membrane; Nucleolus; Phosphatase.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0073-47212017000100231
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