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	Provedor de dados BJMBR (1) Autor Andersen,M.L. (1) Papale,L.A. (1) Perry,J.C. (1) Tufik,S. (1) Palavra-chave Atropine (1) Cholinergic (1) Electroencephalography (1) Ethanol (1) Paradoxical sleep (1) Pilocarpine (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2008 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Participation of the cholinergic system in the ethanol-induced suppression of paradoxical sleep in rats BJMBR Papale,L.A.; Andersen,M.L.; Perry,J.C.; Tufik,S.. Sleep disturbance is among the many consequences of ethanol abuse in both humans and rodents. Ethanol consumption can reduce REM or paradoxical sleep (PS) in humans and rats, respectively. The first aim of this study was to develop an animal model of ethanol-induced PS suppression. This model administered intragastrically (by gavage) to male Wistar rats (3 months old, 200-250 g) 0.5 to 3.5 g/kg ethanol. The 3.5 g/kg dose of ethanol suppressed the PS stage compared with the vehicle group (distilled water) during the first 2-h interval (0-2 h; 1.3 vs 10.2; P < 0.001). The second aim of this study was to investigate the mechanisms by which ethanol suppresses PS. We examined the effects of cholinergic drug pretreatment. The cholinergic system was chosen... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cholinergic; Atropine; Pilocarpine; Ethanol; Paradoxical sleep; Electroencephalography. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000900007 Registros recuperados: 1 Primeira ... 1 ... Última

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