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| Registros recuperados: 34 | |
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| Allendorf,SD; Albas,A; Cipriano,JRB; Antunes,JMAP; Appolinário,CM; Peres,MG; da Rosa,AR; Sodré,MM; Megid,J. |
| Current knowledge on bat lyssavirus infections in their native hosts is limited and little is known about the virulence, virus dissemination and transmission among free-living insectivorous bats. The present study is a brief description of rabies virus (RABV) dissemination in tissues of a naturally infected pregnant southern yellow bat (Lasiurus ega) and its fetuses, obtained by reverse-transcriptase polymerase chain reaction (RT-PCR). The RT-PCR was positive in samples from the brain, salivary gland, tongue, lungs, heart, kidneys and liver. On the other hand, the placenta, three fetuses, spleen, intestine and brown fat tissue tested negative. This research demonstrated the absence of rabies virus in the fetuses, thus, in this specific case, the... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Rabies; Bats; Vertical transmission; RT-PCR. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200014 |
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| Dantas-Torres,F.. |
| Bats are very interesting animals: they are the unique flying mammals, have developed a highly sophisticated echolocation system, and have become specialized to eat different types of diets. Hematophagous (vampire) bats are those specialized to feed solely on blood and have served as a source of inspiration for researchers as well as for writers. Vampire bat attacks on humans have moved from the realm of science fiction to reality in Latin America and bats (including non-hematophagous ones) have assumed an important role in the transmission of rabies virus to humans. This article discusses the emerging role of bats as rabies virus transmitters, with particular emphasis on the role of hematophagous bats in the epidemiology of human rabies in Latin America.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Epidemiology; Disease transmission; Chiroptera. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000200002 |
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| Zhen-Yu,Qu; Guo-Wei,Li; Qiao-Ge,Chen; Peng,Jiang; Chang,Liu; Alfred,Lam. |
| Abstract Background Rabies is very common in People’s Republic of China. Each year thousands of people die because of this disease, but rabies diagnosed in pregnancy is very rare. Case Presentation In this study, we report the case of a pregnant woman who was infected with the rabies virus after a dog bite. The symptoms of rabies appeared in labor and she died after pregnancy. Her baby and husband did not develop the disease. Conclusion The phenomenon that the newborn infant was healthy may be related to the protective role of placenta in resisting the invasion of the rabies virus or the absence of systemic viremia. The prompt administration of vaccines and anti-rabies immunoglobulin to the infant may have also contributed to his survival. |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Rabies; Pregnant; Newborn baby. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100502 |
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| Ayres,J. A.; Barraviera,B.; Calvi,S. A.; Carvalho,N. R.; Peraçoli,M. T. S.. |
| Rabies is considered a fatal disease once clinical symptoms have developed. The aim of this study was to evaluate epidemiological aspects and immune response in patients attacked by domestic and wild animals and subjected to post-exposure rabies treatment with equine serum and associated vaccine. Thirty-three patients were evaluated; they were between 13 and 65 years old, 75.8% were male and 24.2% female, and from the Botucatu neighborhood. Twenty healthy control individuals with the same age range were also studied. Specific antibodies to equine immunoglobulins and IFN-gamma, IL-2, IL-4, and IL-10 production were evaluated by ELISA. IgM, IgE, IgG and subclasses, and rabies virus antibodies serum levels were determined by nephelometry and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Anti-rabies prophylaxis; Immunoglobulins; Cytokines. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000300008 |
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| Langoni,H.; Lima,K.; Menozzi,B. D.; Silva,R. C.. |
| Rabies is a viral disease of mammals transmitted through the bite of a rabid animal. A frugivorous adult male bat, Artibeus lituratus, family Phyllostomidae, was diagnosed as positive to rabies by direct immunofluorescence (DIF) and mouse inoculation test (MIT) of the bat's brain, both performed at the School of Veterinary Medicine and Animal Husbandry - FMVZ, UNESP, Botucatu, São Paulo State, Brazil. The animal collided with the window of a commercial establishment in the urban area during the day. With regard to DIF, a high amount of Negri bodies of several sizes was observed in the brain. The spleen and right kidney presented some Negri bodies too. In relation to MIT, the mice presented paralysis in the 7th day, and died in the day after with several... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Southeastern Brazil; Rabies; Phyllostomidae; Frugivorous bat. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000100010 |
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| Babboni,Selene Daniela; Costa,Hení Falcão da; Martorelli,Luzia de Fátima Alves; Kataoka,Ana Paula de Arruda Geraldes; Victoria,Cassiano; Padovani,Carlos Roberto; Modolo,José Rafael. |
| Background Rabies, a zoonosis found throughout the globe, is caused by a virus of theLyssavirus genus. The disease is transmitted to humans through the inoculation of the virus present in the saliva of infected mammals. Since its prognosis is usually fatal for humans, nationwide public campaigns to vaccinate dogs and cats against rabies aim to break the epidemiological link between the virus and its reservoirs in Brazil.Findings During 12 months we evaluated the active immunity of dogs first vaccinated (booster shot at 30 days after first vaccination) against rabies using the Fuenzalida-Palácios modified vaccine in the urban area of Botucatu city, São Pauto state, Brazil. Of the analyzed dogs, 54.7% maintained protective titers (≥0.5 IU/mL) for 360 days... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Dogs; Vaccination; Revaccination; Annual vaccination campaign; Fuenzalida-Palácios. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200602 |
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| Vigerelli,Hugo; Sciani,Juliana M.; Pereira,Patricia M. C.; Lavezo,Aline A.; Silva,Andrea C. R.; Collaço,Rita C. O.; Rocha,Thalita; Bueno,Thais C.; Pimenta,Daniel C.. |
| Abstract Background: Between 40,000-70,000 people die yearly of rabies, an incurable disease. Besides post-bite vaccination, no treatment is available for it. Methods: First, virus dilution for antiviral effects in mice was determined. Then, animals were treated as follows: control (NaCl 250 µL/animal/day); bufotenine (0.63, 1.05 and 2.1 mg in 250 µL of NaCl/animal/day); rabies (10-6,82CVS dilution); and test (10-6,82 CVS dilution and bufotenine, in the above-mentioned doses). Animals were observed daily for 21 days or until the 3rd stage of rabies infection. Twitch-tension and liposome studies were applied to understand the possible interaction of bufotenine with receptors, particularly acetylcholine. Results: Bufotenine was able to increase the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Rabies therapy; Bufotenine. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100303 |
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| Consales,C. A.; Pereira,C. A.; Passos,E. C.; Carrieri,M. L.; Galina,N. M. F.; Sant'Anna,O. A.. |
| The relationship among the phenotypes resistance to infection, virus replication in the brain and isotype production was investigated in genetically modified High (H) or Low (L) antibody responder mouse lines. Although they express the same innate susceptibility to rabies infection, these lines differ as to different viral replication rates in the central nervous system and L mice showed a higher permissible state. After intramuscular infection with the Pasteur rabies strain (PV), the H-L interline differences on the earlier stage of virus replication were 1000 and 80 folds on days 5 and 6, respectively. The isotype profile in sera of the experimentally infected mice reflected an interline difference of 25 folds for IgG2a throughout the infection period,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Infection; Isotypes; Nervous system. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000300007 |
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| Albas,A.; Fontolan,O. L.; Pardo,P. E.; Bremer Neto,H.; Sartori,A.. |
| In this study, we compared the levels of neutralizing antibodies induced by inactivated rabies vaccine in cattle by using three alternative immunization procedures. Forty-five bovines (breed nelore) were then organized in three groups (A, B and C, with 15 animals/group). Group A received only one vaccine dose at day zero and Group B received the first dose at day zero and then another dose at day 30 (early booster). Group C was also immunized with two doses; however, the booster was postponed until day 180 after the first dose (delayed booster). Blood samples were withdrawn at days zero (before the first dose) and 30, 210, 390, and 540 after the beginning of immunization and the antibody titers were evaluated by mouse neutralization test. The protocol used... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Vaccine; Cattle; Antibody; Neutralization. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000300010 |
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| Consales,C. A.; Bolzan,V. L.. |
| Among the diseases of viral origin, rabies is unique in its distribution and range of victims since it can afflict all warm-blooded animals. The interaction between the virus and the host population has facilitated the survival of the disease. The rabies virus (RV) has not changed in any significant way and has been capable of taking advantage of conditions suited to the continuance of rabies. Infection by RV is invariably lethal in the absence of protective immune response which, however, can contribute to the pathogenesis of rabies. Proinflammatory cytokines might affect, directly or indirectly, the levels of neurotrophins, growth factors, neurotransmitters and neurotoxins in the brain by activating glia, neurons, and vascular and immune cells. Although... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Immunopathology; Clinical aspects; Treatment. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000100002 |
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| Ayres,JA; Paiva,BSR; Barraviera,B. |
| This analysis aimed to identify characteristics of accidents that would, probably, provoke rabies infection. A total of 14,409 survey questionnaires for surveillance of human rabies from the Brazilian Information System for Disease Notification (SINAN), from 2000 to 2005, were analyzed. Regarding demographics, it was observed that 7,377 (51.5%) of the victims were white, 4,458 (30.93%) were children and 8,008 (55.58%) were males. Urban cases were prevalent (88.10%) while dogs were the animals most frequently involved in accidents, in 11,700 cases (81.19%). Bites (84.35%) and scratches (19.15%) were the most prevalent exposure types, and occurred predominantly on victims' extremities (38.79%). The prophylactic measure taken in 6,179 cases comprised... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Post-exposure prophylaxis; Anti-rabies serotherapy. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000100016 |
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| Brandão,PE. |
| Rabies is a viral zoonotic infectious disease that affects mammals and is caused by genotypes/species of the Lyssavirus genus (Rhabdoviridae, Mononegavirales), with the genotype 1 (classic rabies virus - RABV) being the most prevalent. Despite continuous efforts, rabies is still an incurable disease that causes thousands of deaths amongst humans worldwide. Due to a wide range of hosts and the different evolutionary paths of RABV in each host, several host-specific variants have arisen in an ongoing process. The result of RABV replication in nervous tissues may lead to two opposite clinical outcomes, i.e., paralytic/dumb form and encephalitic/furious one. The paralytic form creates dead-end hosts mainly amongst herbivores, while the furious form of the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Transmission; Disease ecology; Epidemiology; Immune response. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000200003 |
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| Vigerelli,Hugo; Sciani,Juliana Mozer; Jared,Carlos; Antoniazzi,Marta Maria; Caporale,Graciane Maria Medeiros; Silva,Andréa de Cássia Rodrigues da; Pimenta,Daniel C. |
| Background Rabies is a fatal zoonotic neglected disease that occurs in more than 150 countries, and kills more than 55.000 people every year. It is caused by an enveloped single stranded RNA virus that affects the central nervous system, through an infection initiated by the muscular nicotinic acetylcholine receptor, according to many authors. Alkaloids, such as acetylcholine, are widespread molecules in nature. They are present in numerous biological fluids, including the skin secretion of many amphibians, in which they act (together with proteins, peptides and steroids) as protection agents against predators and/or microorganisms. Among those amphibians that are rich in alkaloids, there is the genus Rhinella.Methods Bufotenine was isolated from Rhinela... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Rhinella; Bufotenine; Alkaloids; Toxins; Mass spectrometry. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200336 |
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| Ogunkoya, A. B.; Osinubi, M. O.V.; Garba, A.; Audu, S. W.; Atuman, Y. J.; Ehimiyein, A. M.. |
| Official reporting of rabies in Nigeria started in 1912. The National Veterinary Research Institute (NVRI), Vom, within the last 77 years, confirmed 4809 cases of animal rabies in Nigeria. Rabies control through immunization programs has crashed woefully and consequently, the rabies situation has become chaotic and confounding. Locally, only 2,137,615 doses of dog anti-rabies vaccines were produced between 1956 and 2005 (average 43,625 per year) by NVRI, Vom. Dog population in Nigeria is currently estimated at 8 million. In the last 20 years of research and follow ups on rabies and associated problems, only 10% of the dogs’ population received anti-rabies immunization. Within the immunized dogs, rabies outbreaks occurred frequently. Evidences on the trend... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Rabies problem; Rabies virus; Apparently healthy dogs; Vaccination; Nigeria Rabies; Rabies problem; Rabies virus; Apparently healthy dogs; Vaccination; Nigeria. |
| Ano: 2013 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/2534 |
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| da Silva, Viviane Alcântara; Gamon, Thais Helena Martins; da Silva, Andréa de Cássia Rodrigues; Caporale, Graciane Maria Medeiros; Chaves, Luciana Botelho; Scheffer, Karin Corrêa. |
| The National Programme for Rabies Prevention aims to maintainimmunogenic protective levels in vaccinated animals, with titersof neutralizing antibodies (VNA) ≥ 0.5 IU / mL. The aim of thisstudy was to evaluate, according to age, race, and the periodof vaccination and blood collection, the immune response indogs that received a single dose of rabies vaccine virus in cellculture. In this study 432 samples received at the Pasteur Instituteof São Paulo in the triennium 2009-2011 were analyzed. Datawere analyzed and the evaluation of the VNA to rabies virus wasperformed by rapid fluorescent inhibition test foci (RFFIT). Of thetotal samples analyzed, 21.76% did not have protective titers.Among these, 67.02% samples were considered puppies andwhen the interval... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neutralizing antibodies; Immune response; Dogs; Rabies; RFFIT; Anticorpos neutralizantes; Resposta imune; Cães; Raiva; RFFIT. |
| Ano: 2014 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/23105 |
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| Registros recuperados: 34 | |
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