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The sleep-wakefulness cycle of Wistar rats with spontaneous absence-like epilepsy Biological Sciences
André, Edison Sanfelice; Bruno-Neto, Rafael; Valle, Angela Cristina do; Timo-Iaria, César.
Possible interactions between the sleep-wakefulness cycle and a new kind of spontaneous epilepsy, expressed as absence-like seizures and spike-wave bursts in FMUSP rats, are evaluated. The electro-oscillograms of some cortical and subcortical regions of the brain were recorded, as well as head, rostrum/vibrissae and eye movements. Recordings were performed uninterruptedly during 24 hours. The seizures were mostly concentrated in the wakefulness state but they could occur in any other phase, including paradoxical sleep. After the seizure, the rats usually returned to the same phase that was interrupted, although they often returned to wakefulness. There was an intense fragmentation of the sleep-wakefulness cycle. The incidence of each cycle phase was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: 2.07.02.01-9 epilepsy; Absence seizures; Spike-wave; Sleep; Wakefulness; Rats Neurofisiologia.
Ano: 2015 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/26908
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