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| Registros recuperados: 10 | |
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| TAKAHASHI, Hiroto; HANEDA, Shingo; KAYANO, Mitsunori; MATSUI, Motozumi; 羽田, 真悟; 茅野, 光範; 松井, 基純. |
| Because the establishment of pregnancy begins at the uterine horn ipsilateral to the corpus luteum (ipsi-horn) in cattle, levels of progesterone (P4) and receptor expression in the endometrial tissue, which regulate the intrauterine environment for embryo development, may differ between the ipsi-horn and the uterine horn contralateral to corpus luteum (contra-horn). The aim of the present study was to determine the endometrial tissue P4 concentrations and nuclear progesterone receptor (PGR), progesterone receptor membrane component 1 (PGRMC1) and PGRMC2 mRNA expressions in the cranial and middle parts of the uterine horns during the luteal phase. The results showed higher endometrial tissue P4 concentrations in the cranial part of the ipsi-horn than in... |
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Palavras-chave: Bovine; Progesterone; Receptor; Uterus. |
| Ano: 2016 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4364 |
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| Lambais,Marcio Rodrigues. |
| Arbuscular mycorrhiza (AM) are the most widespread symbiotic associations between plant roots and soil fungi. AM can contribute to increasing the survival and fitness of plants to limiting environments mostly due to their ability in improving nutrient uptake from the soil solution. Despite their ecological significance, the mechanisms controlling AM development and functioning are largely unknown. The obligate mutualistic nature of the arbuscular mycorrhizal fungi (AMF) has hampered the advances on the understanding and application of the symbiosis. Significant alterations in the genetic programs of both symbionts are required for the successful establishment of an AM, and complex signaling and signal transduction mechanisms are likely involved. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: DMI gene; Symbiosis; Branching factor; Receptor; Calcium spiking. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162006000400013 |
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| LIXA,CAROLINA; MUJO,AMANDA; ANOBOM,CRISTIANE D.; PINHEIRO,ANDERSON S.. |
| Bacteria are able to synchronize the population behavior in order to regulate gene expression through a cell-to-cell communication mechanism called quorum sensing. This phenomenon involves the production, detection and the response to extracellular signaling molecules named autoinducers, which directly or indirectly regulate gene expression in a cell density-dependent manner. Quorum sensing may control a wide range of biological processes in bacteria, such as bioluminescence, virulence factor production, biofilm formation and antibiotic resistance. The autoinducers are recognized by specific receptors that can either be membrane-bound histidine kinase receptors, which work by activating cognate cytoplasmic response regulators, or cytoplasmic receptors... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Autoinducer; Bacteria; Quorum sensing; Receptor; Structure. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000502189 |
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| Jurkiewicz,Aron; Caricati-Neto,Afonso; Jurkiewicz,Neide H.. |
| The term functionomics (Amin 2003, Neumann et al. 2004) refers to a postgenomic integrated Systems Biology (Attur et al. 2002) using a multidimensional approach for cells, tissues and organs. It considers current or future involvement among genomics, proteomics or metabolomics, including the main factors that cause biological responses and modulation under different conditions. Our objective in the present review is to summarize the contemporary understanding of functionomics of smooth muscle pharmacology, based on the results obtained on the pregenomic era during several years in our laboratory. The present approach is based on the knowledge of the dynamics of the receptor system, which comprises a cascade of phenomena, leading from the drug... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Functionomics; Receptor; Smooth muscle; Genomic. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300022 |
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| Zheng,Qi; Xu,Jun; Gao,Huihui; Tao,Ran; Li,Wei; Shang,Shiqiang; Gu,Weizhong. |
| Human cytomegalovirus is a ubiquitous pathogen that infects the majority of the world's population. After long period of time co-evolving with human being, this pathogen has developed several strategies to evade host immune surveillance. One of the major trick is encoding homologous to those of the host organism or stealing host cellular genes that have significant functions in immune system. To date, we have found several viral immune analogous which include G protein coupled receptor, class I major histocompatibility complex and chemokine. Chemokine is a small group of molecules which is defined by the presence of four cysteines in highly conserved region. The four kinds of chemokines (C, CC, CXC, and CX3C) are classified based on the arrangement of 1 or 2... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chemokine; Cytomegalovirus; Receptor; Immune. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000400403 |
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| Machado,L.J.C.; Marubayashi,U.; Reis,A.M.; Coimbra,C.C.. |
| We have shown that the renin-angiotensin system (RAS) is involved in glucose homeostasis during acute hemorrhage. Since almost all of the physiological actions described for angiotensin II were mediated by AT1 receptors, the present experiments were designed to determine the participation of AT1 receptors in the hyperglycemic action of angiotensin II in freely moving rats. The animals were divided into two experimental groups: 1) animals submitted to intravenous administration of angiotensin II (0.96 nmol/100 g body weight) which caused a rapid increase in plasma glucose reaching the highest values at 5 min after the injection (33% of the initial values, P<0.01), and 2) animals submitted to intravenous administration of DuP-753 (losartan), a... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Glycemia; Angiotensin II; DuP-753; AT1; Receptor. |
| Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001000018 |
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| Martins,V.R.. |
| Prions are an unconventional form of infectious agents composed only of protein and involved in transmissible spongiform encephalopathies in humans and animals. The infectious particle is composed by PrPsc which is an isoform of a normal cellular glycosyl-phosphatidylinositol (GPI) anchored protein, PrPc, of unknown function. The two proteins differ only in conformation, PrPc is composed of 40% <FONT FACE="Symbol">a</FONT> helix while PrPsc has 60% ß-sheet and 20% <FONT FACE="Symbol">a</FONT> helix structure. The infection mechanism is trigged by interaction of PrPsc with cellular prion protein causing conversion of the latter's conformation. Therefore, the infection spreads because new PrPsc molecules are generated exponentially... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Prion; Transmissible spongiform encephalopathies; PrPc; Receptor. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000700009 |
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| Nephrogenic diabetes insipidus (NDI) is a rare disease characterized by renal inability to respond properly to arginine vasopressin due to mutations in the vasopressin type 2 receptor (V2(R)) gene in affected kindreds. In most kindreds thus far reported, the mode of inheritance follows an X chromosome-linked recessive pattern although autosomal-dominant and autosomal-recessive modes of inheritance have also been described. Studies demonstrating mutations in the V2(R) gene in affected kindreds that modify the receptor structure, resulting in a dys- or nonfunctional receptor have been described, but phenotypically indistinguishable NDI patients with a structurally normal V2(R) gene have also been reported. In the present study, we analyzed exon 3 of the... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Vasopressin; Receptor; Polymorphism; Diabetes insipidus; Receptor gene polymorphism. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000400002 |
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| Registros recuperados: 10 | |
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