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Evaluation of Decellularized Matrix and ß-Tricalcium Phosphate as Biomaterials for Bone Neoformation: In vivo Study International Journal of Morphology
Muñoz-Ruíz,Abraham; Silva-Benítez,Erika; Soto-Sainz,Eduardo; Cerda-Cristerna,Bernardino; Ortiz-Magdaleno,Mariné; Pozos-Guillen,Amaury; Flores,Héctor.
The aim of this study was to evaluate histologically the effect of two biomaterials, a biomaterial derived from porcine Urinary submucosa Bladder Matrix (UBM) and beta-TriCalcium Phosphate (ß-TCP), on bone defects. Twenty male New Zealand rabbits were used; the models were divided in two groups: the UBM group; the ß-TCP group, and a Negative Control (NC) group. Five-mm defects were created in the femur of each model and then the different biomaterials were set in place depending on each group. At 4 and 8 weeks, the animals in the models were sacrificed and samples of the defect site were collected to perform a Hematoxylin and Eosin stain (H&E). Histologically, ß-TCP group at 4 and 8 weeks presented neoformation of bone-like and cartilage-like tissue,...
Tipo: Journal article Palavras-chave: Urinary bladder matrix; Bone regeneration; Biomaterial; SS-tricalcium phosphate.
Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000300003
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