Data/hora: 09/06/2024 19:12:40

Provedor de dados: 	16	
País: 	Netherlands	
Título: 	Evolution of species-specific major seminal fluid proteins in placental mammals by gene death and positive selection	
Autores: 	Meslin, C.; Laurin, M.; Callebaut, I.; Druart, X.; Monget, P.	
Data: 	2015	
Ano: 	2015	
Palavras-chave: 	Molecular evolution; Multivariate phylogenetic pairwise comparisons; Reproductive isolation; Speciation; Comparative biology; Pseudogenisation; 42.64; 42.13; 42.70.	
Resumo: 	The seminal fluid is a complex substance composed of a variety of secreted proteins and has been shown to play an important role in the fertilisation process in mammals and also in Drosophila. Several genes under positive selection have been documented in some rodents and primates. Our study documents this phenomenon in several other mammalian taxa. We study the evolution of genes that encode for 20 proteins that are quantitatively predominant in the seminal fluid of at least one out of seven domestic animal species. We analyse the amino acid composition of these proteins for positive selection and for the presence of pseudogenes. Genes that disappeared through pseudogenisation include KLK2 in cattle, horse and mice. Traces of positive selection are found in seven genes. The identified amino acids are located in regions exposed to the protein surface, suggesting a role in the interaction of gametes, with possible impact on the process of speciation. Moreover, we found no evidence that the predominance of proteins in seminal fluid and their mode of evolution are correlated, and the uncoupled patterns of change suggest that this result is not due solely to lack of statistical power.	
Tipo: 	Article / Letter to the editor	
Identificador: 	http://www.repository.naturalis.nl/record/575180

http://www.repository.naturalis.nl/document/609926

http://www.repository.naturalis.nl/document/609931

http://www.repository.naturalis.nl/document/609932

http://www.repository.naturalis.nl/document/609933

http://www.repository.naturalis.nl/document/609934

http://www.repository.naturalis.nl/document/609936

http://www.repository.naturalis.nl/document/609937

http://www.repository.naturalis.nl/document/609939

http://www.repository.naturalis.nl/document/610159	
Formato: 	application/pdf

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Fonte: 	Contributions to Zoology (1875-9866) vol.84 (2015) nr.3 p.217	
Fonte: 	(c) Naturalis