Data/hora: 13/06/2024 16:11:57

Provedor de dados: 	17	
País: 	United Kingdom	
Título: 	Solubilization of M2 Transmembrane Peptide of Influenza A in Pure Water: Implications for Emergence of Proteins and Protein-embedded Primeval Membranes in Unsalted Oceans	
Autores: 	Jianxing Song; Linlin  Miao.	
Data: 	2012-01-11	
Ano: 	2012	
Palavras-chave: 	Chemistry; Molecular Cell Biology; Evolutionary Biology.	
Resumo: 	We demonstrated that M2 transmembrane peptide, one of the most hydrophobic sequences in nature, can be solublized to at least ~100 &amp;#xb5;M in unsalted water without any lipid molecules. Strikingly, the M2 peptide also forms a highly-helical conformation in water which remains almost unchanged even at 95 &amp;#xba;C, as characterized by CD spectroscopy. Our result has critical implications in understanding emergence of proteins and protein-embedded primeval membranes in unsalted oceans.	
Tipo: 	Manuscript	
Identificador: 	http://precedings.nature.com/documents/6773/version/1

oai:nature.com:10101/npre.2012.6773.1

http://hdl.handle.net/10101/npre.2012.6773.1	
Fonte: 	Nature Precedings	
Fonte: 	Creative Commons Attribution 3.0 License