Data/hora: 03/06/2024 04:52:04

Provedor de dados: | Nature Precedings
País: | United Kingdom
Título: | Trichoplax, the simplest known animal, contains an estrogen-related receptor: Implications for the evolution of vertebrate and invertebrate estrogen receptors
Autores: | Michael E. Baker.
Data: | 2008-05-06
Ano: | 2008
Palavras-chave: | Developmental Biology; Ecology; Evolutionary Biology.
Resumo: | Although, as their names imply, vertebrate and invertebrate estrogen receptors [ERs] and estrogen-related receptors [ERRs] are related transcription factors, their evolutionary relationships to each other are not fully understood.  We searched recently sequenced genome of _Trichoplax_, the simplest known animal, and genomes from three lophotrochozoans: _Capitella_, a worm, _Helobdella robusta_, a leech, and _Lottia gigantea_, a snail, to elucidate the origins and evolution of ERs and ERRs.  BLAST found an ERR in _Trichoplax_, but no ER.  BLAST searches of the lophotrochozaons found ERRs in all three and invertebrate ERs in _Capitella_ and _Lottia_, but not in _Helobdella_.  These database searches and a phylogenetic analyses indicate that invertebrate ERs arose in a protostome, and vertebrate ERs arose later in deuterostome.
Tipo: | Manuscript

Identificador:

http://precedings.nature.com/documents/1863/version/1

oai:nature.com:10101/npre.2008.1863.1

http://hdl.handle.net/10101/npre.2008.1863.1

Fonte: | Nature Precedings
Fonte: | Creative Commons Attribution 3.0 License