Data/hora: 12/06/2024 14:02:04

Provedor de dados: | Nature Precedings
País: | United Kingdom
Título: | Multifunction moonlighting and intrinsically disordered proteins: Information catalysis, nonrigid molecule symmetries, and the &amp;#x27;logic gate&amp;#x27; spectrum
Autores: | Rodrick Wallace.
Data: | 2011-09-14
Ano: | 2011
Palavras-chave: | Biotechnology; Cancer; Chemistry; Developmental Biology; Molecular Cell Biology; Pharmacology; Bioinformatics; Evolutionary Biology.
Resumo: | Intrinsically disordered proteins (IDP) appear far more likely to engage in functional moonlighting than well-structured proteins. The recent use of nonrigid molecule theory to address IDP structure and dynamics produces this result directly: Mirror image subgroup or subgroupoid tiling matching of the molecular fuzzy lock-and-key can be much richer for IDPs since the number of possible group or groupoid symmetries can grow exponentially with molecule length, while tiling matching for 3D structured proteins is relatively limited. A simple information catalysis model suggests how this mechanism can produce a vast spectrum of biological &amp;#x27;logic gates&amp;#x27; having subtle properties far beyond familiar AND, OR, XOR, etc. behaviors. Inferring the general from the particular, the analysis adds weight to arguments that a fundamental defining characteristic of the living state is the operation of chemical or other cognitive processes at virtually every scale and level of organization.
Tipo: | Manuscript

Identificador:

http://precedings.nature.com/documents/6413/version/1

oai:nature.com:10101/npre.2011.6413.1

http://hdl.handle.net/10101/npre.2011.6413.1

Fonte: | Nature Precedings
Fonte: | Creative Commons Attribution 3.0 License