Data/hora: 13/06/2024 02:28:49

Provedor de dados: 	17	
País: 	United Kingdom	
Título: 	Neem leaf glucosamine stimulates Interleukin-2 (IL-2) in swiss albino mice	
Autores: 	Santhosh Kumar Venugopalan; Navaratnam Viswesharan; Rajasekaran Aiyalu; Nair N K.	
Data: 	2011-04-24	
Ano: 	2011	
Palavras-chave: 	Pharmacology.	
Resumo: 	Neem leaf glucosamine-mediated immune stimulation was studied in male swiss albino mice. Mice were treated with three doses of Neem leaf glucosamine (266, 400 and 800 &amp;#xb5;g/30gm mouse, intraperitoneal injection) one dose per week for four weeks. At doses of 266, 400 and 800 &amp;#xb5;g/30gm mouse a significant increase in Interleukin-2 in mice serum was observed when compared to the control group and also an increase in relative organ weight of the thymus was observed but there was a mild increase in liver and kidney weights. The immune stimulatory response of Neem leaf glucosamine was also observed in T-lymphocyte proliferation. Overall, Neem leaf glucosamine showed a stimulatory effect on immune functions in mice. The immunostimulatory effect of Neem leaf glucosamine as reported in this study will have special relevance for the prophylactic and potential therapeutic treatment of various infectious diseases and antitumor activity.	
Tipo: 	Manuscript	
Identificador: 	http://precedings.nature.com/documents/5923/version/1

oai:nature.com:10101/npre.2011.5923.1

http://hdl.handle.net/10101/npre.2011.5923.1	
Fonte: 	Nature Precedings	
Fonte: 	Creative Commons Attribution 3.0 License