Data/hora: 10/06/2024 09:18:02

Provedor de dados: | Obihiro University of Agriculture and Veterinary Medicine Academic Repository (OAK)
País: | Japan

Título:

上顎の扁平上皮癌に対するCUL療法により良好なQOLを維持している犬の1例

A Dog with Oral Squamous Cell Carcinoma Treated by CUL Therapy

Autores: | 野田, 桂; 嶋田, 照雅; 小川, 高; 伊藤, 位一; 大橋, 文人; NODA, Katsura; SHIMADA, Terumasa; OGAWA, Takashi; ITOH, Norikazu; OHASHl, Fumihito.
Data: | 2009
Ano: | 2009
Palavras-chave: | Cisplatin; CUL treatment; Squamous cell carcinoma; シスプラチン; CUL療法; 扁平上皮癌.
Resumo: | In this report，a canine carcinoma was so far successfully treated by CUL treatment， an injection of suspention of an anti-cancer drug and contrast medium directly into the tumor. A nine-year-old spayed female golden retriever was brought to us with the main complaint of a mass in the oral cavity. The cytodiagnosis of the tumor was a squamous cell carcinoma. After palliative surgical resection of the mass， the dog was treated with intratumoral administration of cisplatin. The release of cisplatin was slowed by mixing it with poppyseed oil ethylesteres iodide (CUL treatment). After the CUL treatment was started， there was little growth of the twnor and no systemic side effects. A good QOL was maintained for 24 months after discovery of the mass. This case demonstrated that CUL treatment is a useful option for inhibitation of the growth of an oral squamous cell carcinoma and preservation of the patient dog's QOL. 犬の上顎に発生した扁平上皮癌に対して腫瘤の姑息的外科切除を行った後に，ヨード化ケシ油脂肪酸エチルエステルとアミドトリゾ酸ナトリウムメグルミンの添加によって吸収遅延処理したシスプラチンを用いた局所抗癌治療（CUL療法）を計18回実施した。本症例の治療経過は良好で，腫瘍の増大は非常に遅くなり，全身性の副作用も認められず，治療開始後18カ月が経過しているが良好なQOLを維持している。以上のことから，CUL療法は口腔内扁平上皮癌の増大抑制とQOL維持を目的とした治療の選択肢の1つとして有用な方法であると考えられた。
Idioma: | Japonês
Identificador: | http://ir.obihiro.ac.jp/dspace/handle/10322/2765
Editor: | 鳥取県動物臨床医学研究所
Formato: | application/pdf
Fonte: | 鳥取県動物臨床医学研究所