Data/hora: 06/06/2024 03:34:27

Provedor de dados: | 19
País: | Japan
Título: | A novel neuropeptide Y neuronal pathway linking energy state and reproductive behavior
Autores: | Muroi, Yoshikage; Ishii, Toshiaki.
Data: | 2016-10
Ano: | 2016
Palavras-chave: | Neuropeptide Y; Hypothalamus; Dorsal raphe nucleus; Reproductive behavior.
Resumo: | Animals consume energy for reproduction, as well as survival. Excess or insufficient energy investment into reproduction, respectively, threatens the survival of parents or leads to the failure of reproduction. Management of energy consumption in reproduction is important, not only for the success of the process, but also for the survival of the parents. Reproductive behaviors, such as mating and parental behavior, are indispensable for achieving each event of reproduction including gametogamy, parturition, and lactation. Therefore, reproductive behavior is one of the important factors in managing energy consumption for reproduction. Orexigenic and anorexigenic molecules in the hypothalamus have been implicated in the regulation of reproductive functions. An orexigenic neuropeptide, neuropeptide Y (NPY), has been also implicated in the regulation of both reproduction and energy state of animals. In this review, we will first summarize the neuronal mechanism for regulating reproductive functions by orexigenic and anorexigenic molecules in the hypothalamus. Second, we will focus on the NPY neuronal pathways regulating reproductive behavior in the intra- and extra-hypothalamic brain areas. We will highlight the NPY neuronal pathway from the arcuate nucleus to the dorsal raphe nucleus as a novel extra-hypothalamic pathway for energy state-dependent regulation of reproductive behavior. Finally, we will propose a biological significance of the extra-hypothalamic NPY neuronal pathway, which plays an important role in the associative control of feeding and reproductive behaviors. (C) 2016 Elsevier Ltd. All rights reserved.
Idioma: | Inglês

Identificador:

http://ir.obihiro.ac.jp/dspace/handle/10322/4530

info:doi/10.1016/j.npep.2016.09.002

Editor: | Elsevier
Fonte: | This accepted manuscript is licensed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. &lt;http://creativecommons.org/lisenses/by-nc-nd/4.0/&gt;