Data/hora: 11/06/2024 14:11:21

Provedor de dados: 	19	
País: 	Japan	
Título: 	Vitamin C Deficiency Fails to Protect Mice from Malaria	
Autores: 	HERBAS, Maria Shirley; SUZUKI, Hiroshi; 鈴木, 宏志.	
Data: 	2010	
Ano: 	2010	
Palavras-chave: 	Free radical; Malaria; Vitamin C.	
Resumo: 	Nutritional deficiencies are frequent in malaria-endemic areas. It seems that micronutrient antioxidants play an important role in malaria parasite’s proliferation. Thus, the effect of vitamin C deficiency on malaria infection was examined in mice. When vitamin C deficient mice, L-gulono-γ-lactone oxidase gene knockout mice which are unable to synthesize ascorbic acid, were infected with a lethal dose of Plasmodium berghei NK65-infected red blood cells, the knockout mice showed similar parasitemia kinetics and survival rates as wild-type mice. The results indicate that deficiency of vitamin C might not affect the development of the malaria parasite in mice.	
Idioma: 	Inglês	
Identificador: 	http://ir.obihiro.ac.jp/dspace/handle/10322/3016	
Editor: 	日本実験動物学会	
Formato: 	application/pdf	
Fonte: 	日本実験動物学会