Data/hora: 10/06/2024 15:23:06

Provedor de dados: | 2
País: | Brazil

Título:

Arginine metabolism in uricotelic species - doi: 10.4025/actascianimsci.v32i4.10990

Arginine metabolism in uricotelic species - doi: 10.4025/actascianimsci.v32i4.10990

Autores: | Fernandes, Jovanir Inês Müller; Universidade Federal do Paraná; Murakami, Alice Eiko; UEM.
Data: | 2010-10-25
Ano: | 2010
Palavras-chave: | Carbamoyl phosphatase synthetase; Creatine; Immune system; Nitric oxide; Polyamines; Urea cycle carbamoyl phosphatase synthetase; Creatine; Immune system; Nitric oxide; Polyamines; Urea cycle.
Resumo: | Due to the lack of a complete urea cycle, uricotelic species, such as broilers, are not able to synthesize de novo arginine (Arg), thus depending exclusively on dietary Arg. High levels of dietary lysine (Lys) increase the demand for Arg because of the antagonistic relationship between these amino acids. The Arg-Lys antagonism promotes an expressive increase in the renal Arg activity and consequently induces the degradation of Arg and the decrease in the activity of glycine amidinotransferase, an enzyme that uses Arg in the synthesis of muscle creatin. Arg is considered an important modulator of immunological and physiological processes. The degradation of Arg produces ornithine, a precursor of polyamines that are key to cell division, DNA synthesis, and cell cycle regulation. Arg participates in the synthesis of nitric oxide (NO), a highly reactive free radical in cells and membranes and participates in several cell processes, including in neurotransmission and immune response. Arg is also considered a potent secretagogue of insulin, growth hormone, and IGF-I in the blood stream. Exclusively vegetarian diets may not provide an adequate supply of Arg, which is required for maximum production and for the immune system of current broiler lineages.
Idioma: | Português

Identificador:

http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/10990

10.4025/actascianimsci.v32i4.10990

Editor: | Editora da Universidade Estadual de Maringá

Formato:

application/pdf

application/pdf

Fonte:

Acta Scientiarum. Animal Sciences; v. 32, n. 4 (2010); 357-366

Acta Scientiarum. Animal Sciences; v. 32, n. 4 (2010); 357-366

Fonte:

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DECLARAÇÃO DE ORIGINALIDADE E CESSÃO DE DIREITOS AUTORAIS  Declaro que o presente artigo é original, não tendo sido submetido à publicação em qualquer outro periódico nacional ou internacional, quer seja em parte ou em sua totalidade. Declaro, ainda, que uma vez publicado na revista Acta Scientiarum. Animal Sciences, editada pela Universidade Estadual de Maringá, o mesmo jamais será submetido por mim ou por qualquer um dos demais co-autores a qualquer outro meio de divulgação científica. Através deste instrumento, em meu nome e em nome dos demais co-autores, porventura existentes, cedo os direitos autorais do referido artigo à Universidade Estadual de Maringá e declaro estar ciente de que a não observância deste compromisso submeterá o infrator a sanções e penas previstas na Lei de Proteção de Direitos Autorias (Nº9609, de 19/02/98).