Data/hora: 07/06/2024 16:38:04

Provedor de dados: 	Acta Scientiarum: Biological Sciences	
País: 	Brazil	
Título: 	Effect of fermentation conditions on the production of hyaluronic acid by Streptococcus zooepidemicus ATCC 39920	
Autores: 	Pan, Nicole Caldas; Vignoli, Josiane Alessandra; Baldo, Cristiani; Pereira, Hanny Cristina Braga; Silva, Rui Sérgio dos Santos Ferreira; Celligoi, Maria Antonia Pedrine Colabone.	
Data: 	2015-10-01	
Ano: 	2015	
Palavras-chave: 	Bioquímica de microrganismos physical factors; Nutritional factors; Glycosaminoglycans; Factorial design; Microbial production. Fermentação.	
Resumo: 	The production of hyaluronic acid by Streptococcus zooepidemicus ATCC 39920 with varying rates of pH (6.0, 7.0, 8.0), temperature (34; 37; 40°C), agitation (100, 150, 200 rpm), glucose (10, 20, 30 g L-1) and yeast extract concentration (10, 20, 30 g L-1) was evaluated by statistical approaches. The best conditions for the production of hyaluronic acid was pH 8.0, 37°C and 100 rpm in a medium containing 30 g L-1 glucose and yeast extract, for a production of 0.787 g L-1. Temperature, pH and yeast extract were significant variables (p &lt; 0.05). Yeast extract and pH had a positive effect on the production of the polymer. Lactate, formate and acetate synthesis were also analyzed. Current assay showed the feasibility of statistical tools to optimize the physical and nutritional parameters for the production of hyaluronic acid and the improvement of the fermentation process. 	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/28176

10.4025/actascibiolsci.v37i4.28176	
Editor: 	Universidade Estadual De Maringá	
Relação: 	http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/28176/pdf_80	
Formato: 	application/pdf	
Fonte: 	Acta Scientiarum. Biological Sciences; v. 37, n. 4 (2015); 411-417

Acta Scientiarum. Biological Sciences; v. 37, n. 4 (2015); 411-417

1807-863X

1679-9283