Data/hora: 04/06/2024 15:09:30

Provedor de dados: | 3
País: | Brazil

Título:

Toxicity at the cellular level of artificial synthetic flavorings

Toxicity at the cellular level of artificial synthetic flavorings

Autores: | Sales, Ila Monize Sousa; Oliveira, Jussara Damascena de; Santos, Fabelina Karollyne Silva dos; Feitoza, Lidiane de Lima; Sousa, João Marcelo de Castro e; Peron, Ana Paula.
Data: | 2016-12-08
Ano: | 2016
Palavras-chave: | Flavorings; Cell division; Cell aberrations; Cytotoxicity; Genotoxicity flavorings; Cell division; Cell aberrations; Cytotoxicity; Genotoxicity.
Resumo: | The goal of the present study was to evaluate the cytotoxicity and genotoxicity of artificial synthetic flavoring agents Cookie and Tutti-frutti. To this end, root meristem cells of Allium cepa L. were exposed to these substances in exposure times of 24 and 48 hours using individual doses of 0.3; 0.6 and 0.9 mL and doses combined as follows: 0.3 mL + 0.3 mL; 0.6 mL and 0.9 mL + 0.6 mL + 0.9 mL. After applying the treatments, root meristems were fixed, hydrolyzed, stained and analyzed a total of 5,000 cells using an optical microscope to evaluate each dose and combined treatment. All three doses of Cookie flavoring and combined treatments significantly inhibited cell division of the tissue studied. Doses of Tutti-Frutti caused no change in cell division rate. In addition, doses of both flavorings and treatments combining these solutions induced cell aberrations in a significant number of cells to the A. cepa system. Therefore, under these analytical conditions, Cookie flavoring and combined doses were cytotoxic and genotoxic, and Tutti-Frutti flavoring, although non-cytotoxic, demonstrated genotoxic action.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês

Identificador:

http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/30751

10.4025/actascibiolsci.v38i3.30751

Editor: | Universidade Estadual De Maringá

Relação:

http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/30751/pdf

http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/downloadSuppFile/30751/11804

Formato: | application/pdf

Fonte:

Acta Scientiarum. Biological Sciences; v. 38, n. 3 (2016); 297-303

Acta Scientiarum. Biological Sciences; v. 38, n. 3 (2016); 297-303

1807-863X

1679-9283

Fonte: | Direitos autorais 2016 Acta Scientiarum. Biological Sciences