Data/hora: 03/06/2024 17:21:38

Provedor de dados: | 36
País: | Brazil
Título: | Bioactive dihydroxyfuranonaphthoquinones from the bark of Tabebuia incana A.H. Gentry (Bignoniaceae) and HPLC analysis of commercial pau d'arco and certified T.incana bark infusions
Autores: | Morais,Sabrina Kelly Reis de; Silva,Suniá Gomes; Portela,Cíntia Nicácio; Nunomura,Sergio Massayoshi; Quignard,Etienne Louis Jacques; Pohlit,Adrian Martin.
Data: | 2007-01-01
Ano: | 2007
Palavras-chave: | Artemia franciscana Leach 5-hydroxy-2-(1-hydroxyethyl)naphtho[2; 3-b]furan-4; 9-dione; 8-hydroxy-2-(1-hydroxyethyl)naphtho[2; 3-b]furan-4; 9-dione.
Resumo: | Tabebuia incana A.H. Gentry (Bignoniaceae) is a tree from the Brazilian Amazon having medicinal uses and is one several Tabebuia spp. known as pau d'arco or palo de arco in this region. Fractionation of the bark ethanolic extract afforded a mixture of 5 and 8-hydroxy-2-(1-hydroxyethyl)naphtho[2,3-b]furan-4,9-diones (1 and 2, respectively) identified on the basis of nuclear magnetic resonance (NMR), infrared (IR) and mass (MS) spectra, whose in vitro antimalarial and antitumor activity have been shown previously. This is the first study on T. incana bark, and 2 are described in this species for the first time. Also, high performance liquid chromatography (HPLC) analysis of T. incana bark tea revealed the presence of the 1 + 2 mixture peak corresponding to a concentration in the range 10-6-10-5 M. The chromatograms of teas prepared from commercial pau d' arco and T. incana bark were also studied and the presence of the 1 + 2 peak has potential for quality control of commercial plant materials.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672007000100011
Editor: | Instituto Nacional de Pesquisas da Amazônia
Relação: | 10.1590/S0044-59672007000100011
Formato: | text/html
Fonte: | Acta Amazonica  v.37 n.1 2007
Fonte: | info:eu-repo/semantics/openAccess