Data/hora: 04/06/2024 00:29:36

Provedor de dados: | 36
País: | Brazil
Título: | In vitro studies of the anthelmintic activity of Picrolemma sprucei Hook. f. (Simaroubaceae)
Autores: | Nunomura,Rita de Cássia Saraiva; Silva,Ellen Cristina Costa da; Oliveira,Denilson Ferreira; Garcia,Adriana Mello; Boeloni,Jankerle Neves; Nunomura,Sergio Massayoshi; Pohlit,Adrian Martin.
Data: | 2006-01-01
Ano: | 2006
Palavras-chave: | Picrolemma pseudocoffea Ducke; Haemonchus contortus; Neosergeolide; Isobrucein B; Caferana.
Resumo: | 1300 ppm (1.3 g / L), water and ethanol extracts prepared from stems or roots of Picrolemma sprucei Hook. f. were lethal (85-90 % mortality) in vitro to Haemonchus contortus (Barber Pole Worm) larvae, a gastrointestinal nematode parasite found in domestic and wild ruminants. Neosergeolide and isobrucein B were isolated in 0.0083 and 0.0070 % yield from dry, ground P. sprucei stems (0.89 kg). Neosergeolide, isobrucein B and the anthelmintic drug standard levamisole all caused comparable mortality rates (68-77 %) in vitro to H. contortus at similar concentrations (81-86 ppm). The anthelmintic activity of P. sprucei infusions (teas), alcohol extracts, and neosergeolide and isobrucein B, has therefore been demonstrated for the first time.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672006000300006
Editor: | Instituto Nacional de Pesquisas da Amazônia
Relação: | 10.1590/S0044-59672006000300006
Formato: | text/html
Fonte: | Acta Amazonica  v.36 n.3 2006
Fonte: | info:eu-repo/semantics/openAccess