Data/hora: 13/06/2024 02:12:54

Provedor de dados: 	Anais da Academia Brasileira de Ciências	
País: 	Brazil	
Título: 	Synthesis, characterization and antimicrobial activity of Cr (III), Co (II) and Ni (II) complexes with 2-thiazoline-2-tiol derivative ligands against bacteria and yeasts of clinical importance	
Autores: 	HERRERA,KARINA M.S.; FERREIRA,LORENA S.; BRAGA,ALYSSON V.; SOUZA,JULIANO P.; ANDRADE,JÉSSICA T.; SOARES,ADRIANA C.; SOARES,LUIS F.; CHAGAS,RAFAEL C.R.; FERREIRA,JAQUELINE M.S.	
Data: 	2019-01-01	
Ano: 	2019	
Palavras-chave: 	1; 2-bis-bis (2-thiazolin-2-isulfanyl) ethane antimicrobial activity hidrotris (2-mercaptothiazolyl) borate complexes.	
Resumo: 	Abstract: Four novel Cr (III), Co (II) and Ni (II) complexes with 2-thiazoline-2-tiol derivative ligands were synthesized and characterized using elemental, physiochemical, and spectroscopy analytical methods. The results showed the formation of ligands coordinated by sulfur atoms of the C = S bond to the L1 ligand and by the sulfur atom of the C-S bond and/or nitrogen of the intra C-ring bond of the L2 ligand. The activity of the complexes against Gram-negative, Gram-positive bacteria and yeasts of clinical importance was evaluated by broth microdilution method. The best result was obtained to L2-Ni compound against E. cloacae (Minimal Inhibitory Concentration (MIC) = 62.5 µg/mL). Additionally, the compounds showed anti-Candida activity (MIC values ranging from 250 to 500 µg/mL), except the L1-Cr that was not active against any tested microorganism.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000700803	
Editor: 	Academia Brasileira de Ciências	
Relação: 	10.1590/0001-376520181077	
Formato: 	text/html	
Fonte: 	Anais da Academia Brasileira de Ciências  v.91 n.4 2019	
Fonte: 	info:eu-repo/semantics/openAccess