Data/hora: 02/06/2024 01:19:47

Provedor de dados: 	Anais da Academia Brasileira de Ciências	
País: 	Brazil	
Título: 	Immune System Dysfunction in the Elderly	
Autores: 	FUENTES,EDUARDO; FUENTES,MANUEL; ALARCÓN,MARCELO; PALOMO,IVÁN.	
Data: 	2017-03-01	
Ano: 	2017	
Palavras-chave: 	Aging; Immunosenescence; Adaptive immunity; Innate immunity; Inflammation.	
Resumo: 	ABSTRACT Human aging is characterized by both physical and physiological frailty that profoundly affects the immune system. In this context aging is associated with declines in adaptive and innate immunity established as immunosenescence. Immunosenescence is a new concept that reflects the age-associated restructuring changes of innate and adaptive immune functions. Thus elderly individuals usually present chronic low-level inflammation, higher infection rates and chronic diseases. A study of alterations in the immune system during aging could provide a potentially useful biomarker for the evaluation of immune senescence treatment. The immune system is the result of the interplay between innate and adaptive immunity, yet the impact of aging on this function is unclear. In this article the function of the immune system during aging is explored.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100285	
Editor: 	Academia Brasileira de Ciências	
Relação: 	10.1590/0001-3765201720160487	
Formato: 	text/html	
Fonte: 	Anais da Academia Brasileira de Ciências  v.89 n.1 2017	
Fonte: 	info:eu-repo/semantics/openAccess