Data/hora: 04/06/2024 00:59:18

Provedor de dados: | 42
País: | Brazil
Título: | Molluscicidal activity of 2-hydroxy-[1,4]naphthoquinone and derivatives
Autores: | Camara,Celso A.; Silva,Tania M.S.; da-Silva,Thiago G.; Martins,Rodrigo M.; Barbosa,Ticiano P.; Pinto,Angelo C.; Vargas,Maria D.
Data: | 2008-06-01
Ano: | 2008
Palavras-chave: | Biomphalaria glabrata Artemia salina toxicity quinones schistosomiasis molluscicidal activity lawsone 1; 4-naphthoquinone.
Resumo: | The toxic profile of lawsone (2-hydroxy-[1,4]naphthoquinone) and a series of [1,4]naphthoquinone derivatives was evaluated against the brine shrimp Artemia salina and against the mollusk Biomphalaria glabrata, the main transmitting vector of schistosomiasis in Brazil. Of the seventeen compounds tested nine fell below the threshold of 100 µg/mL set for potential molluscicidal activity by the World Health Organization. As a general rule derivatives with non-polar substituents presented the highest molluscicidal activities. These substances showed significant toxicity in A. salina lethality bioassay.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652008000200011
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/S0001-37652008000200011
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.80 n.2 2008
Fonte: | info:eu-repo/semantics/openAccess