Data/hora: 08/06/2024 18:38:06

Provedor de dados: | Anais da Academia Brasileira de Ciências
País: | Brazil
Título: | Physicochemical/photophysical characterization and angiogenic properties of Curcuma longa essential oil
Autores: | ARAÚJO,LILHIAN A.; ARAÚJO,RAFAEL G.M.; GOMES,FLÁVIA O.; LEMES,SUSY R.; ALMEIDA,LUCIANE M.; MAIA,LAURO J.Q.; GONÇALVES,PABLO J.; MRUÉ,FÁTIMA; SILVA-JUNIOR,NELSON J.; MELO-REIS,PAULO R. DE.
Data: | 2016-01-01
Ano: | 2016
Palavras-chave: | Angiogenic activity; Curcumin; Essential oil; Physicochemical.
Resumo: | ABSTRACT This study analyzed the physicochemical and photophysical properties of essential oil of Curcuma longa and its angiogenic potential. The results showed that curcumin is the main fluorescent component present in the oil, although the amount is relatively small. The experimental chorioallantoic membrane model was used to evaluate angiogenic activity, showing a significant increase in the vascular network of Curcuma longa and positive control groups when compared to the neutral and inhibitor controls (P &lt;0.05), but no significant difference was found between Curcuma longa essential oil and the positive control (P &gt;0.05). Histological analysis showed extensive neovascularization, hyperemia and inflammation in the positive control group and Curcuma longa when compared to other controls (P &lt;0.05), characteristic factors of the angiogenesis process. In conclusion, Curcuma longa oil showed considerable proangiogenic activity and could be a potential compound in medical applications.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000501889
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/0001-3765201620150600
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.88 n.3 suppl.0 2016
Fonte: | info:eu-repo/semantics/openAccess