Data/hora: 02/06/2024 16:20:52

Provedor de dados: | 42
País: | Brazil
Título: | The structural molecular biology network of the State of São Paulo, Brazil
Autores: | Barbosa,João A.R.G.; Netto,Luis E.S.; Farah,Chuck S.; Schenkman,Sergio; Meneghini,Rogério.
Data: | 2006-06-01
Ano: | 2006
Palavras-chave: | Structural genomics; Protein crystallography; Nuclear magnetic resonance; Protein structure.
Resumo: | This article describes the achievements of the Structural Molecular Biology Network (SMolBNet), a collaborative program of structural molecular biology, centered in the State of São Paulo, Brazil, and supported by São Paulo State Funding Agency (FAPESP). It gathers twenty scientific groups and is coordinated by the scientific staff of the Center of Structural Molecular Biology, at the National Laboratory of Synchrotron Light (LNLS), in Campinas. The SMolBNet program has been aimed at 1) solving the structure of proteins of interest related to the research projects of the groups. In some cases, the choice has been to select proteins of unknown function or of possible novel structure obtained from the sequenced genomes of the FAPESP genomic program; 2) providing the groups with training in all the steps of the protein structure determination: gene cloning, protein expression, protein purification, protein crystallization and structure determination. Having begun in 2001, the program has been successful in both aims. Here, four groups reveal their participation in the program and describe the structural aspects of the proteins they have selected to study.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652006000200006
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/S0001-37652006000200006
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.78 n.2 2006
Fonte: | info:eu-repo/semantics/openAccess