Data/hora: 03/06/2024 18:11:30

Provedor de dados: 	Anais da Academia Brasileira de Ciências	
País: 	Brazil	
Título: 	Investigation on the effects of guava (Psidium guajava L.) infusions on germination, root tips and meristematic cells of Latuca sativa	
Autores: 	Luber,Jaquelini; Palmieri,Marcel J.; Botelho,Carolina M.; Rinaldo,Daniel; Andrade-Vieira,Larissa F.	
Data: 	2015-06-01	
Ano: 	2015	
Palavras-chave: 	Citogenetoxicity; Root growth; Mitotic index; Seed germination; IC50.	
Resumo: 	Guava (Psidium guajava L.) is a plant often employed in popular medicine. Recently several studies have alerted about the toxicity of substances present in medicinal plants, which can pose risks to the human health. In this sense, the present work aimed to investigate the phytotoxic, cytotoxic and genotoxic action of three guava varieties - Paluma, Pedro Sato and Roxa ("purple") - on the plant test system Lactuca sativa L. Thus, macro- and microscopic evaluations were carried out for five infusion concentrations (2.5, 5.0, 10.0, 20.0 and 40.0 g.L-1) prepared from each variety. Distilled water was used as negative control. Chromatographic and spectroscopic analysis by HPLC-PAD indicated that the chemical composition of the infusion of Roxa is different than that of the infusions of the varieties Paluma and Pedro Sato. It was observed that seed germination and root growth in L. sativa exposed to infusions decreased with increasing infusion concentration, regardless of the tested cultivar. For the mitotic index, no statistical differences were observed. On the other hand, a significant increase in the frequency of cell cycle alterations was verified, especially for the highest concentrations tested. The cytogenotoxic effect was significant. Therefore, guava should not be used indiscriminately in popular medicine.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000200903	
Editor: 	Academia Brasileira de Ciências	
Relação: 	10.1590/0001-3765201520140286	
Formato: 	text/html	
Fonte: 	Anais da Academia Brasileira de Ciências  v.87 n.2 2015	
Fonte: 	info:eu-repo/semantics/openAccess