Data/hora: 10/06/2024 04:49:43

Provedor de dados: 	45	
País: 	Brazil	
Título: 	Serological responses in sheep injected with plasmids encoding bovine herpesvirus 1 (BHV-1) gD glycoprotein	
Autores: 	Cândido,A.L.; Resende,M.; Bessa,L.R.G.; Leite,R.C.	
Data: 	2003-06-01	
Ano: 	2003	
Palavras-chave: 	Bovine herpesvirus-1.2a; Glycoprotein D gene; DNA vaccine; ELISA.	
Resumo: 	A genetic vaccine consisting of the bovine herpesvirus-1.2a (BHV-1.2a) glycoprotein D (gD) gene under the control of the cytomegalovirus immediate-early promoter/enhancer was generated and administered to sheep intramuscularly in the neck. All animals developed serum antibodies which recognized the homologous antigen (BHV-1.2a strain BH-83) and also exhibited cross-reactivity against the heterologous antigen (BHV-5 strain EVI-190). Three intramuscularly injections were given but serological responses were not improved after the second inoculation. Specific antibodies were detected against BHV-1.2a until at least 12 months after the first inoculation. However, the capacity to induce antibodies against BHV-5 was lower and of shorter duration than to BHV-1.2a.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352003000300002	
Editor: 	Universidade Federal de Minas Gerais, Escola de Veterinária	
Relação: 	10.1590/S0102-09352003000300002	
Formato: 	text/html	
Fonte: 	Arquivo Brasileiro de Medicina Veterinária e Zootecnia  v.55 n.3 2003	
Fonte: 	info:eu-repo/semantics/openAccess