Data/hora: 04/06/2024 03:40:26

Provedor de dados: | 45
País: | Brazil
Título: | Experimental Trypanosoma evansi infection in donkeys: hematological, biochemical and histopathological changes
Autores: | Cadioli,F.A.; Marques,L.C.; Machado,R.Z.; Alessi,A.C.; Aquino,L.P.C.T.; Barnabé,P A.
Data: | 2006-10-01
Ano: | 2006
Palavras-chave: | Donkey; Experimental infection; Trypanosoma evansi; Trypanosomiasis.
Resumo: | Five adult donkeys were experimentally infected with Brazilian strain of Trypanosoma evansi originally isolated from a naturally infected dog to study the hematological biochemical and histopathological alterations during the evolution of the disease. The course of the experimental infection was followed up to 145 days. Hematological analyses of the infected donkeys revealed a marked decline in hemoglobin, packed-cell volume, and erythrocyte count. Anemia was observed after successive peaks of parasitemia. Biochemical analyses showed increased levels of icterus index, serum globulins and decreased serum albumin and glucose values. All infected donkeys revealed enlargement of spleen and its white pulp, enlargement of mediastinal lymph nodes and lungs congestion. The main histopathological features consisted of meningoencephalitis. Demyelination in some areas of the cerebellum pediculus and neuropil vacuolization were observed. This study showed that donkeys infected with a Brazilian strain of T. evansi developed a chronic disease.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000500008
Editor: | Universidade Federal de Minas Gerais, Escola de Veterinária
Relação: | 10.1590/S0102-09352006000500008
Formato: | text/html
Fonte: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia  v.58 n.5 2006
Fonte: | info:eu-repo/semantics/openAccess