Data/hora: 09/06/2024 11:36:18

Provedor de dados: 	Arquivo Brasileiro de Medicina Veterinária e Zootecnia	
País: 	Brazil	
Título: 	Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis	
Autores: 	Rodrigues,A.B.F; Ristow,P; Santos,A.S.O; Lilenbaum,W; Fonseca,L.S; Carvalho,C.B; Carvalho,E.C.Q.	
Data: 	2010-12-01	
Ano: 	2010	
Palavras-chave: 	Bovino; Paratuberculose; Hepatite; Histopatologia.	
Resumo: 	Samples from intestines, liver, and lymph nodes were collected from a dairy steer with clinical suspicion of paratuberculosis. The samples were processed for histologic examination with hematoxylin-eosin and Zihel-Neelsen (ZN) staining for the detection of acid-fast bacilli (AFB), and submitted to immunohistochemistry (IHC). Macroscopic changes were observed in the small intestines, with thickening and corrugation of the mucosa. The main microscopic changes were found in small intestines, lymph vessels in the mesentery, and mesenteric lymph nodes characterized by enteritis, lymphangiectasia, and lymphadenitis. Liver presented with granulomatous hepatitis, an uncommon histopathological feature for paratuberculosis. The clinical features associated with positive culture of Mycobacterium avium subsp. paratuberculosis and detection of AFB by ZN and IHC in the cytoplasm of macrophages (epithelioid) in the intestinal mucosa and submucosa, lymph nodes, and liver were important to confirm the diagnosis of paratuberculosis.	
Tipo: 	Info:eu-repo/semantics/other	
Idioma: 	Português	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352010000600029	
Editor: 	Universidade Federal de Minas Gerais, Escola de Veterinária	
Relação: 	10.1590/S0102-09352010000600029	
Formato: 	text/html	
Fonte: 	Arquivo Brasileiro de Medicina Veterinária e Zootecnia  v.62 n.6 2010	
Fonte: 	info:eu-repo/semantics/openAccess