Data/hora: 16/06/2024 06:36:05

Provedor de dados: | 45
País: | Brazil
Título: | Esporotricose experimental sistêmica em ratos Wistar: avaliação hematológica e perfil hepático
Autores: | Meinerz,A.R.M.; Antunes,T.A.; Silva,F.V.; Xavier,M.O.; Cleff,M.B.; Meireles,M.C.A.
Data: | 2008-08-01
Ano: | 2008
Palavras-chave: | Rato; Esporotricose experimental; Sporotrix schenckii; Enzimas hepáticas.
Resumo: | Alanine aminotransferase (ALT) and alkaline phosphatase (AP) hepatic enzymes, hematological values, and total plasmatic proteins (TPP) of 12 Wistar rats with systemic experimental sporotrichosis were evaluated. Inoculation was performed at 2x10³ cells of S. schenckii/ml. The values ranged from 35 to 48UI/l for ALT and 67 to 251.3UI/l for AP. Fifty percent of the AP values were above the physiological limits. TPP was elevated in 66.7% (8/12) of the rats with values varying from 7.9 to 8.5g%. In 75% (9/12) of the animals, it was observed that hemoglobin and red blood cells count were below the physiologic limits, and 8.3% (1/12) of the animals showed anemia masked by dehydration. At the necropsy, it was observed local and/or disseminated nodular lesions. At the histological analysis, cells compatible to S. schenckii were found. The observed alterations are aggravating factors for the recurrence and treatment of the mycosis.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Português
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000400038
Editor: | Universidade Federal de Minas Gerais, Escola de Veterinária
Relação: | 10.1590/S0102-09352008000400038
Formato: | text/html
Fonte: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia  v.60 n.4 2008
Fonte: | info:eu-repo/semantics/openAccess