Data/hora: 10/06/2024 15:04:31

Provedor de dados: | 47
País: | Argentina
Título: | Effects of the ascorbic acid supplementation on NADH-diaphorase myenteric neurons in the duodenum of diabetic rats
Autores: | Pereira,Marli Aparecida Dos Santos; Bagatin,Maria Claúdia; Zanoni,Jacqueline Nelisis.
Data: | 2006-08-01
Ano: | 2006
Palavras-chave: | Diabetes mellitus; Ascorbic acid; Myenteric neurons.
Resumo: | We assessed the ascorbic acid (AA) supplementation on the myenteric neurons in the duodenum of rats. Fifteen rats with 90 days of age were divided into three groups: control (C), diabetics (D) and ascorbic acid treated diabetics (DA). After 120 days of daily treatment with AA, the duodenum was submitted to the NADH-diaphorase (NADH-d) histochemical technique, which allowed us to evaluate the neuronal density in an area of 8.96 mm² for each duodenum, and also to measure the cellular profile area of 500 neurons per group. The supplementation promoted an increase on AA levels. The neuronal density (p &lt;0.05) was higher in the group DA when compared to group D. There were no significant differences in the neuronal areas, when we compared groups C (204 ± 16.5) and D (146.3 ± 35.84) to groups D and DA (184.5 ± 5.6) (p&amp;gt;0.05). The AA-supplementation avoided the density reduction of the NADHd myenteric neurons in the duodenum of diabetic rats.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452006000200005
Editor: | Sociedad Latinoamericana de Microscopía Electrónica.; Centro Regional de Investigaciones Científicas y Tecnológicas (Mendoza, Argentina)
Formato: | text/html
Fonte: | Biocell  v.30 n.2 2006
Fonte: | info:eu-repo/semantics/openAccess