Data/hora: 04/06/2024 01:26:41

Provedor de dados: | Biological Research
País: | Chile
Título: | The Ca2+ pump inhibitor, thapsigargin, inhibits root gravitropism in Arabidopsis thaliana
Autores: | URBINA,DANIELA C; SILVA,HERMAN; MEISEL,LEE A.
Data: | 2006-01-01
Ano: | 2006
Palavras-chave: | Arabidopsis thaliana; Ca2+-ATPases; Calcium; Gravitropism; Thapsigargin; Root.
Resumo: | Thapsigargin, a specific inhibitor of most animal intracellular SERCA-type Ca2+ pumps present in the sarcoplasmic/endoplasmic reticulum, was originally isolated from the roots of the Mediterranean plant Thapsia gargancia L. Here, we demonstrate that this root-derived compound is capable of altering root gravitropism in Arabidopsis thaliana. Thapsigargin concentrations as low as 0.1 µM alter root gravitropism whereas under similar conditions cyclopiazonic acid does not. Furthermore, a fluorescently conjugated thapsigargin (BODIPY FL thapsigargin) suggests that target sites for thapsigargin are located in intracellular organelles in the root distal elongation zone and the root cap, regions known to regulate root gravitropism
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000200011
Editor: | Sociedad de Biología de Chile
Formato: | text/html
Fonte: | Biological Research  v.39 n.2 2006