Data/hora: 04/06/2024 04:18:25

Provedor de dados: 	48	
País: 	Chile	
Título: 	Effects of isoflavone on oxidative stress parameters and homocysteine in postmenopausal women complaining of insomnia	
Autores: 	BRANDÃO,LETÍCIA C; HACHUL,HELENA; BITTENCOURT,LIA R; BARACAT,EDMUND C; TUFIK,SERGIO; D'ALMEIDA,VÂNIA.	
Data: 	2009-01-01	
Ano: 	2009	
Palavras-chave: 	Homocysteine; Isoflavones; Insomnia; Menopause; Oxidative stress.	
Resumo: 	Sleep disorders have an increased incidence after menopause. The objective of this work was to evaluate the effects of isoflavone on some oxidative stress markers in postmenopausal women complaining of insomnia. Women aged between 50-65 years (n=38) were recruited and assigned to a double-blind placebo controlled study for 4 months. The treated group received 100 mg/day of isoflavones. Blood collections were conducted on three different occasions to assess total glutathione; superoxide dismutase and catalase in erythrocytes; lipid peroxidation; and homocysteine plasma concentrations. No differences between the groups were observed. However, all the patients seem to improve their oxidative stress status and homocysteine concentration after treatment. Superoxide dismutase activity was correlated with age and time of menopause at the beginning of the treatment, but these correlations were no longer observed by the end of the study. Soy isoflavones were not able to overcome the placebo effect for either oxidative stress parameters or homocysteine concentrations.	
Tipo: 	Journal article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300002	
Editor: 	Sociedad de Biología de Chile	
Formato: 	text/html	
Fonte: 	Biological Research  v.42 n.3 2009