Data/hora: 03/06/2024 17:52:12

Provedor de dados: | 48
País: | Chile
Título: | Anatomy of corpus callosum in prenatally malnourished rats
Autores: | Olivares,Ricardo; Morgan,Carlos; Pérez,Hernán; Hernández,Alejandro; Aboitiz,Francisco; Soto-Moyano,Rubén; Gil,Julio; Ortiz,Alexis; Flores,Osvaldo; Gimeno,Miguel; Laborda,Jesús.
Data: | 2012-01-01
Ano: | 2012
Palavras-chave: | Corpus callosum; Prenatal malnutrition; Rat; Splenium.
Resumo: | The effect of prenatal malnutrition on the anatomy of the corpus callosum was assessed in adult rats (45-52 days old). In the prenatally malnourished animals we observed a significant reduction of the corpus callosum total area, partial areas, and perimeter, as compared with normal animals. In addition, the splenium of corpus callosum (posterior fifth) showed a significant decrease of fiber diameters in the myelinated fibers without changing density. There was also a significant decrease in diameter and a significant increase in density of unmyelinated fibers. Measurements of perimeter's fractal dimensions from sagittal sections of the brain and corpus callosum did not show significant differences between malnourished and control animals. These findings indicate that cortico-cortical connections are vulnerable to the prenatal malnutrition, and suggest this may affect interhemispheric conduction velocity, particulary in visual connections (splenium).
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000100012
Editor: | Sociedad de Biología de Chile
Formato: | text/html
Fonte: | Biological Research  v.45 n.1 2012