Data/hora: 04/06/2024 12:47:50

Provedor de dados: | 48
País: | Chile
Título: | Characterization and mapping of an informational suppressor in Aspergillus nidulans
Autores: | GRACITE DE MELO FRANZONI,MELISSA; ALVES DE CASTRO-PRADO,MARIALBA AVEZUM.
Data: | 2000-01-01
Ano: | 2000
Palavras-chave: | Aspergillus nidulans; Barren cleistothecia; Informational suppressor; Paromomycin.
Resumo: | The present work was undertaken to characterize a suppressor gene present in a mutant strain of A. nidulans obtained with NTG (N-Methyl-N'-Nitro-N-Nitrosoguanidine). Analyses of this mutant have shown that this suppressor, designated suO1, induces phenotypic co-reversion of several auxotrophic mutations and makes the strain sensitive to aminoglycoside antibiotics and lower temperatures. suO1 has shown to be on linkage group VIII. The vegetative growth of the mutant strain is very unstable because the suppressor gene induces the production of prototrophic mitotic sectors. The strains bearing the suO1 gene produce cleistothecia containing a reduced number of viable ascospores during the sexual cycle. The segregation of the genetic markers has also been observed in the mutant strain self crossed. From the above results it may be concluded that suO1 is an informational suppressor
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000100008
Editor: | Sociedad de Biología de Chile
Formato: | text/html
Fonte: | Biological Research  v.33 n.1 2000