Data/hora: 06/06/2024 05:26:37

Provedor de dados: 	5	
País: 	France	
Título: 	First Evidence of Palytoxin and 42-Hydroxy-palytoxin in the Marine Cyanobacterium Trichodesmium	
Autores: 	Kerbrat, Anne Sophie; Amzil, Zouher; Pawlowiez, Ralph; Golubic, Stjepko; Sibat, Manoella; Darius, Helene Taiana; Chinain, Mireille; Laurent, Dominique.	
Data: 	2011-04	
Ano: 	2011	
Palavras-chave: 	Cyanobacteria; Trichodesmium; Palytoxin; 42-hydroxy-palytoxin; Clupeotoxism.	
Resumo: 	Marine pelagic diazotrophic cyanobacteria of the genus Trichodesmium (Oscillatoriales) are widespread throughout the tropics and subtropics, and are particularly common in the waters of New Caledonia. Blooms of Trichodesmium are suspected to be a potential source of toxins in the ciguatera food chain and were previously reported to contain several types of paralyzing toxins. The toxicity of water-soluble extracts of Trichodesmium spp. were analyzed by mouse bioassay and Neuroblastoma assay and their toxic compounds characterized using liquid chromatography coupled with tandem mass spectrometry techniques. Here, we report the first identification of palytoxin and one of its derivatives, 42-hydroxy-palytoxin, in field samples of Trichodesmium collected in the New Caledonian lagoon. The possible role played by Trichodesmium blooms in the development of clupeotoxism, this human intoxication following the ingestion of plankton-eating fish and classically associated with Ostreopsis blooms, is also discussed.	
Tipo: 	Text	
Idioma: 	Inglês	
Identificador: 	https://archimer.ifremer.fr/doc/00040/15143/12576.pdf

DOI:10.3390/md9040543

https://archimer.ifremer.fr/doc/00040/15143/	
Editor: 	Mdpi Ag	
Formato: 	application/pdf	
Fonte: 	Marine Drugs (1660-3397) (Mdpi Ag), 2011-04 , Vol. 9 , N. 4 , P. 543-560	
Fonte: 	2011 MDPI Publishing

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