Data/hora: 02/06/2024 02:59:00

Provedor de dados: | Institutional Archive of Ifreme (ArchiMer)
País: | France
Título: | Case report of osteomyelitis of the mandible in osteopetrosis and management considerations
Autores: | Allal, Sarah; Rabuel, Valentin; Gengler, Charline; Douchet, Catherine; Allal, Francois; Zwetyenga, Narcisse.
Data: | 2021
Ano: | 2021
Palavras-chave: | Osteomyelitis; Mandible; Case report; Osteopetrosis; Management.
Resumo: | Introduction and importance Osteopetrosis is a poorly known and probably underdiagnosed pathology. It is caused by various genetic abnormalities resulting in osteoclast dysfunction. Functional and aesthetic consequences have a major impact on the patient’s quality of life. Ten percent of osteopetrosis cases develop osteomyelitis that usually involves the mandible. Management of this complication remains complex and often unsatisfactory. Case presentation We report a case of a 62-year-old woman with osteopetrosis, complicated by mandibular osteomyelitis with intra-oral bone exposure and submental fistulas. Management was performed with antibiotic therapy and surgical necrotic resection. This cured the fistulas but the bone exposure persisted. Discussion This case report highlights the difficulty of achieving complete healing of osteomyelitis in osteopetrosis. Antibiotic therapy, surgical management, or even hyperbaric oxygen therapy are required, but must be adapted to the case. A free flap procedure is undesirable but, when it is necessary, a bone marrow transplant could be considered to restore osteoclast function. Conclusion The management of mandibular osteomyelitis in patients with osteopetrosis must adapt to the situation and severity. To avoid most cases of osteomyelitic complications in patients suffering from osteopetrosis, we propose that a preventive strategy of better dental care should be considered.
Tipo: | Text
Idioma: | Inglês

Identificador:

https://archimer.ifremer.fr/doc/00686/79816/82611.pdf

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DOI:10.1016/j.ijscr.2021.105813

https://archimer.ifremer.fr/doc/00686/79816/

Editor: | Elsevier BV
Formato: | application/pdf
Fonte: | International Journal Of Surgery Case Reports (2210-2612) (Elsevier BV), 2021 , Vol. 81 , P. 105813 (5p.)

Fonte:

info:eu-repo/semantics/openAccess

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