Data/hora: 16/06/2024 09:22:55

Provedor de dados: 	5	
País: 	France	
Título: 	Improving the Antioxidant Properties of Calophyllum inophyllum Seed Oil from French Polynesia: Development and Biological Applications of Resinous Ethanol-Soluble Extracts	
Autores: 	Cassien, Mathieu; Mercier, Anne; Thétiot-laurent, Sophie; Culcasi, Marcel; Ricquebourg, Emilie; Asteian, Alice; Herbette, Gaëtan; Bianchini, Jean-pierre; Raharivelomanana, Phila; Pietri, Sylvia.	
Data: 	2021-02	
Ano: 	2021	
Palavras-chave: 	Calophyllum inophyllum L; Tamanu oil; Ethanol-soluble resin extracts; Lipophilic antioxidants; Phenolics; Pyranocoumarins; Antimicrobial; Anti-inflammatory; UV protection; EPR spin trapping.	
Resumo: 	Tamanu oil from Calophyllum inophyllum L. has long been used in traditional medicine. Ethanol extraction was found the best strategy for recovering bioactive compounds from the resin part of Tamanu oil, yielding two neutral and acidic resins fractions with high phenolics, flavonoids and pyranocoumarins concentrations. A further cascade of LPLC/HPLC separations of neutral and acidic resin fractions allowed identifying fifteen metabolites, and among them, calanolide D and 12-oxocalanolide A (both in neutral fraction) were first identified from a natural source. All these extracts, subfractions and isolated metabolites demonstrated increased free radical scavenging, antioxidant, anti-inflammatory, antimicrobial and antimycobacterial activity compared to Tamanu oil and its de-resinated lipid phase. Overall, these results could promote resinous ethanol-soluble Tamanu oil extracts as a useful multifaceted and renewable medicinal resource	
Tipo: 	Text	
Idioma: 	Inglês	
Identificador: 	https://archimer.ifremer.fr/doc/00677/78918/81283.pdf

https://archimer.ifremer.fr/doc/00677/78918/81284.pdf

DOI:10.3390/antiox10020199

https://archimer.ifremer.fr/doc/00677/78918/	
Editor: 	MDPI AG	
Formato: 	application/pdf	
Fonte: 	Antioxidants (2076-3921) (MDPI AG), 2021-02 , Vol. 10 , N. 2 , P. 199 (23p.)	
Fonte: 	info:eu-repo/semantics/openAccess

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