Data/hora: 05/06/2024 02:48:31

Provedor de dados: | 5
País: | France
Título: | Interaction de la bactérie Vibrio harveyi avec son hôte, l'hormeau Haliotis tuberculata : approches physiologiques, cellulaires et moléculaires
Autores: | Travers, Marie-agnes.
Data: | 2008-09-08
Ano: | 2008
Palavras-chave: | Ormeau; Haliotis tuberculata; Bactéries; Vibrio harveyi; Vibriose; Température; Immunité; Reproduction; Hémocytes; MAP Kinases; Plasmide; Virulence; GFP; Abalone; Haliotis tuberculata; Bacteria; Vibrio harveyi; Vibriosis; Temperature; Immunity; Reproduction; Haemocytes; MAP Kinases; Plasmid; Virulence; GFP.
Resumo: | Abalone aquaculture only recently developed in western Europe, but already it has to face numerous pathologies. Since 1998, the natural and farm stocks of Haliotis tuberculata suffer regularly high mortalities, mainly due to the pathogenic bacterium, Vibrio harveyi. The vibriosis of the European abalone, in particular its macroscopic signs, and the conditions necessary for its development have been studied in detail by field and laboratory experiments. We have been able to show the importance of the interplay between water temperature (&gt;17°C), animal physiology (reproduction period) and a pathogenic strain (harbouring the plasmid pVCR1) for the development of this abalone disease. A limited localisation study of the abalone target tissues (gills, muscle and haemolymph) has been performed and a 3 phase disease development model is hypothesized. A clear link between the reproduction period with its accompanying immune deficiency and the animals sensitivity to the pathogen has been established. By a molecular approach, it has been discerned that the virulent V. harveyi strains directly intervene with the animal’s immune system, probably through a partial inhibition of the MAP kinase pathway activation in the haemocyte. Finally, we were also able to show the utmost importance of the pVCR1 plasmid for the virulence phenotype of this pathogenic bacterium.
Tipo: | Text
Idioma: | Francês
Identificador: | http://archimer.ifremer.fr/doc/00176/28729/27196.pdf
Editor: | Université de Bretagne Occidentale, Brest
Relação: | http://archimer.ifremer.fr/doc/00176/28729/
Formato: | application/pdf