Data/hora: 05/06/2024 17:29:18

Provedor de dados: 	5	
País: 	France	
Título: 	Temporal study of estrogenic responses of mussel (Mytilus galloprovinciallis) extracts applied to reporter cell lines	
Autores: 	David, A; Dagnino, S; Pichot, Yves; Munaron, Dominique; Escande, A; Casellas, C; Fenet, H; Gomez, E.	
Data: 	2008-07	
Ano: 	2008	
Palavras-chave: 	ELISA; Reporter cell lines; Mytilus galloprovinciallis; Estradiol; Biomonitoring.	
Resumo: 	In vitro bioassays would facilitate monitoring of estrogen-like compounds in mussels (Mytilus galloprovincialis) since they tend to accumulate lipophilic compounds in their fat and muscle tissue. However, estradiol (E2) steroid (already identified in mussels) could induce false positive responses. This study focuses on temporal variability in estrogenic responses of mussel extracts and the possible relation of this response with E2 levels. The reproductive cycle and growth were thus monitored for six months in sexed mussels. E2 levels were similar between genders and these levels varied with reproductive stages. human estrogen receptor (hER) activities were similar at all stages except in February. E2 present in male and female extracts accounted for part of the hER activation observed, but no correlation was found between E2 levels and hER activities. (C) 2008 Elsevier Ltd. All rights reserved.	
Tipo: 	Text	
Idioma: 	Inglês	
Identificador: 	http://archimer.ifremer.fr/doc/2008/publication-4578.pdf

DOI:10.1016/j.marenvres.2008.02.037	
Editor: 	Elsevier	
Relação: 	http://archimer.ifremer.fr/doc/00000/4578/	
Formato: 	application/pdf	
Fonte: 	Marine Environmental Research (0141-1136) (Elsevier), 2008-07 , Vol. 66 , N. 1 , P. 105-107	
Fonte: 	2008 Elsevier Ltd All rights reserved.