Data/hora: 04/06/2024 03:42:45

Provedor de dados: 	5	
País: 	France	
Título: 	Comportements cellulaires et régulation génétique au cours des réactions d'immunité innée chez la moule Mytilus galloprovincialis	
Autores: 	Li, Hui.	
Data: 	2008-11-27	
Ano: 	2008	
Palavras-chave: 	Mytilus; Haemocyte; Antimicrobial peptides; Polymorphism; Genetic regulation; Innate immunity; Mytilus; Hémocyte; Peptides antimicrobiens; Polymorphisme; Régulation génétique; Immunité innée.	
Resumo: 	The mytiliculture is one of the most important aquaculture in the world, however, little is known on the mussel immune system, which plays a critical role in case of infectious diseases. Like all the other invertebrates, our model, the Mediterranean mussel Mytilus galloprovincialis, possesses only an innate immune system considered to be primitive and non-specific. In the present study, our results showed that the mussel immune system (i) is capable of responding differently to a variety of stimulations, suggesting a specific recognition process; (ii) reacts differently according to the geographic origin of the animals, showing an adaptation to their own environment; (iii) is influenced by the season, which explains the seasonal mortalities; (iv) presents an extended polymorphism of antimicrobial peptides, which increases in turn the number of molecular effectors. In conclusion, the innate immunity system of the mussel appears more complex than suspected and involving polymorphic immune effectors. Moreover, this system is capable of responding specifically to different stimuli, of adaptation to the environment, and is influenced by the season.	
Tipo: 	Text	
Idioma: 	Francês	
Identificador: 	http://archimer.ifremer.fr/doc/2008/these-6241.pdf	
Editor: 	Université de Montpellier 2	
Relação: 	http://archimer.ifremer.fr/doc/00000/6241/	
Formato: 	application/pdf