Data/hora: 08/06/2024 02:38:21

Provedor de dados: | Brazilian Archives of Biology and Technology
País: | Brazil
Título: | Rats offspring exposed to Ipomoea Carnea and handling during gestation: neurochemical evaluation
Autores: | Schwarz,Aline; Hosomi,Rosana Zoriki; Flório,Jorge Camilo; Bernardi,Maria Martha; Górniak,Silvana Lima; Spinosa,Helenice Souza.
Data: | 2007-05-01
Ano: | 2007
Palavras-chave: | Ipomoea carnea; Neurotransmitter; Perinate; Rats; Stress.
Resumo: | The present study evaluated the central monoamine levels of male and female adult rat offspring exposed orally by gavage to 0.0, 0.7, 3.0 and 15.0 mg/kg I. carnea aqueous extract daily, from gestation day (GD) 5 to GD 21. Several alterations in the monoamine activity systems were observed. However, the major differences were noted between the 0.0 mg/kg and the no gavage control groups, showing that alterations showing that alterations were not due to the alterations to the aqueous extract. The control data showed that gavage and handling of dams were stressful enough to produce a significant decline in 3,4-dihydroxyphenylacetic acid (DOPAC) and an increase in vanilmandelic acid (VMA), indicating decreased dopamine (DA) and enhanced norepinephrine (NE) activity, respectively.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000300009
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132007000300009
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.50 n.3 2007
Fonte: | info:eu-repo/semantics/openAccess