Data/hora: 04/06/2024 17:39:38

Provedor de dados: 	52	
País: 	Brazil	
Título: 	Characterization and Cytotoxic Evaluation of Silver and Gold Nanoparticles Produced with Aqueous Extract of Lavandula dentata L. in Relation to K-562 Cell Line	
Autores: 	Justus,Barbara; Arana,Andrés Fernando Montenegro; Gonçalves,Melissa Marques; Wohnrath,Karen; Boscardin,Patrícia Mathias Döll; Kanunfre,Carla Cristine; Budel,Jane Manfron; Farago,Paulo Vitor; Paula,Josiane de Fátima Padilha de.	
Data: 	2019-01-01	
Ano: 	2019	
Palavras-chave: 	Green synthesis; Metallic nanoparticles; Myelogenous leukemia line; Cytotoxic potential; Lamiaceae.	
Resumo: 	Abstract Metallic nanoparticles have great potential as a chemotherapeutic agent. The aim of this study was to develop and characterize silver and gold nanoparticles using a simple method, as well as evaluating the potential cytotoxic activity in relation to the K-562 cell line. For the synthesis, a solution containing the metallic ions was subjected to magnetic stirring with the aqueous extract of Lavandula dentata L. and a change of colour was observed. With the data obtained from the analyses we concluded that the nanoparticles were successfully obtained by a simple and green method using the aqueous extract of L. dentata. The obtained nanoparticles presented a reduced size, a low level of polydispersion, and a homogenous spherical shape. The nanoparticles presented intense and characteristic diffraction peaks, which could be correlated to the planes of the centred cubic structure of the silver and gold. The two formulations presented predominantly crystalline characteristics. The infrared analysis suggested that the amides and alcohols present in the samples may have been responsible for the reduction and limitation of the size and dispersion of the silver and gold nanoparticles. The cytotoxic assay showed that the nanoparticles demonstrated great potential to reduce the cell viability of the K-562 cell line, especially the gold nanoparticles.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100420	
Editor: 	Instituto de Tecnologia do Paraná - Tecpar	
Relação: 	10.1590/1678-4324-2019180731	
Formato: 	text/html	
Fonte: 	Brazilian Archives of Biology and Technology  v.62 2019	
Fonte: 	info:eu-repo/semantics/openAccess