Data/hora: 16/06/2024 01:44:34

Provedor de dados: | 52
País: | Brazil
Título: | Green Tropical Phytoextracts - Promising Anticancer Alternative
Autores: | Khan,Abid Ali; Omer,Kosar Ali; Talib,Ayesha; Ahmed,Haroon; Javed,Mohamad Arshad; Sarmidi,Roji Mohamad.
Data: | 2016-01-01
Ano: | 2016
Palavras-chave: | Labisia pumila; Ficus deltoidea; Anticancer Plant Extract; Prostate cancer.
Resumo: | ABSTRACT The anticancer potential of aqueous extracts of tropical plants Ficus deltoidea and Labisia pumila were tested on human prostate carcinoma (DU145) cells. The effects of these extracts on the cells were observed through several tests such as cytotoxicity MTT assay, trypan blue exclusion assay (for cell viability), fluorescence and morphological observations. Both of the plant extracts had a growth repression effect on the cells with different concentrations. The best concentration (1x10-3 μg/mL) was chosen by determining their cytotoxic effects on human prostate cancer as well as fibroblast (normal) cells. The F. deltoidea extract showed more potency and killed the cells faster than L. pumila. Morphologically both extracts affected the cells in a similar way, i.e. the cells became irregular shaped, detached themselves and kept floating in the medium.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100328
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/1678-4324-2016160062
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.59 2016
Fonte: | info:eu-repo/semantics/openAccess