Data/hora: 10/06/2024 11:24:26

Provedor de dados: | Brazilian Archives of Biology and Technology
País: | Brazil
Título: | Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity
Autores: | Cortez,Lucia Elaine Ranieri; Ferreira,Izabel Cristina Piloto; Lonardoni,Valdrinez Campana; Ferreira,Antonio Gilberto; Vieira,Paulo Cesar; Silva,Maria Fátima das Graças Fernandes da; Fernandes,João Batista; Cortez,Diógenes Aparicio Garcia.
Data: | 2011-02-01
Ano: | 2011
Palavras-chave: | Almeidea coerulea; Rutaceae; Indolopyridoquinazoline alkaloid; Anti-leishmanial activity.
Resumo: | The dichloromethane extract of Almeidea coerulea stems yielded the (11-hydroxyrutaecarpine alkaloid reported for the first time from this species) and the triterpene (28-hydroxy-28, 29-dihydrolupeol). The dictamine, skimianine, sitosterol and stigmasterol were also isolated from methanol extract. Extracellular forms of Leishmania amazonensis (promastigotes) was tested with dichloromethane extract and 28-hydroxy-28, 29-dihydrolupeol with showed anti-leishmanial activity above 0.1 mg/mL and 75µg/mL (inhibited 50% promastigote growth), respectively.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000100008
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132011000100008
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.54 n.1 2011
Fonte: | info:eu-repo/semantics/openAccess