Data/hora: 02/06/2024 12:32:42

Provedor de dados: | Brazilian Archives of Biology and Technology
País: | Brazil
Título: | Immune response after rabies oral immunization in mice
Autores: | Silva,Camila Sloboda Pacheco da; Krüger,Ernesto Renato; Agottani,Jorge Victor Bacila; Oliveira,Rubens Chaguri de; Pereira,Sandro; Penha,Tânia Regina; Ollhoff,Rüdiger Daniel.
Data: | 2013-12-01
Ano: | 2013
Palavras-chave: | Rabies; Oral vaccine; Mice; ELISA.
Resumo: | The objective of this study was to formulate an anti-rabies oral vaccine from the cell culture vaccine PV TECPAR to elicit the production of antibodies against the rabies in mice. A vaccine was developed using 10(7.5) DL50/0.03 ml viral antigens homogenised in lanovaseline to facilitate oral administration. Mice were vaccinated two times for seroconversion. Sera of the vaccinated mice showed a higher level of antibody production than the control group. These results could be used to direct the development of an anti-rabies oral vaccine.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000600006
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132013005000001
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.56 n.6 2013
Fonte: | info:eu-repo/semantics/openAccess